Early hemodynamic impact of SGLT2 inhibitors in overweight cardiometabolic heart failure: beyond fluid offloading to vascular adaptation– a preliminary report

Early hemodynamic impact of SGLT2 inhibitors in overweight cardiometabolic heart failure: beyond fluid offloading to vascular adaptation– a preliminary report

Abstract Background Heart failure (HF) is increasingly recognized as a heterogeneous cardiometabolic disorder, often in the context of overweight/obesity independently from diabetes. Sodium-glucose cotransporter-2 inhibitors (SGLT2i) reduce HF hospitalizations and cardiovascular mortality across eje...

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Main Authors: Nadia Salerno, Jessica Ielapi, Angelica Cersosimo, Isabella Leo, Assunta Di Costanzo, Giuseppe Armentaro, Salvatore De Rosa, Angela Sciacqua, Sabato Sorrentino, Daniele Torella
Format: Article
Language:English
Published: BMC 2025-03-01
Series:Cardiovascular Diabetology
Subjects:
Heart failure
Sodium-glucose cotransporter 2 inhibitors
Hemodynamics
Non-invasive monitoring
Online Access:https://doi.org/10.1186/s12933-025-02699-4
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