Impact of Methamphetamine Abuse: A Rare Case of Rapid Cerebral Aneurysm Growth with Review of Literature
Methamphetamine or “meth” is a sympathomimetic amine of the amphetamine-type substances (ATS) class with an extremely high potential for abuse. Illicitly abused neurostimulants like cocaine and meth predispose patients to the aneurysmal formation with reported rupture at a younger age and in much sm...
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| Format: | Article |
| Language: | English |
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Wiley
2018-01-01
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| Series: | Case Reports in Neurological Medicine |
| Online Access: | http://dx.doi.org/10.1155/2018/1879329 |
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| author | James Fowler Brian Fiani Syed A. Quadri Vladimir Cortez Mudassir Frooqui Atif Zafar Fahad Shabbir Ahmed Asad Ikram Anirudh Ramachandran Javed Siddiqi |
| author_facet | James Fowler Brian Fiani Syed A. Quadri Vladimir Cortez Mudassir Frooqui Atif Zafar Fahad Shabbir Ahmed Asad Ikram Anirudh Ramachandran Javed Siddiqi |
| author_sort | James Fowler |
| collection | DOAJ |
| description | Methamphetamine or “meth” is a sympathomimetic amine of the amphetamine-type substances (ATS) class with an extremely high potential for abuse. Illicitly abused neurostimulants like cocaine and meth predispose patients to the aneurysmal formation with reported rupture at a younger age and in much smaller sized aneurysms. However, very rapid growth of aneurysm within less than 2 weeks with methamphetamine abuse is very rarely observed or reported. In this report, we present a patient with repeated and recurrent meth abuse who demonstrated rapid growth of a pericallosal aneurysm over the period of less than two weeks. The pathophysiology of stroke related to meth and ATS abuse is multifactorial with hypertension, tachycardia, and vascular disease postulated as major mechanisms. The rapid growth of an aneurysm has a high risk of aneurysmal rupture and SAH, which is a neurosurgical emergency and therefore warrants careful consideration and close monitoring. This case confirms the dynamic temporal effects of methamphetamine use on intracranial vessels and this specific neurostimulants association to rapid aneurysmal formation. In light of vascular pathologies the possibility of drug-induced pseudoaneurysm should also be considered in young patients with history of meth abuse. |
| format | Article |
| id | doaj-art-50506a6184b249a1a1e764d61d75eae9 |
| institution | Kabale University |
| issn | 2090-6668 2090-6676 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Neurological Medicine |
| spelling | doaj-art-50506a6184b249a1a1e764d61d75eae92025-02-03T01:24:18ZengWileyCase Reports in Neurological Medicine2090-66682090-66762018-01-01201810.1155/2018/18793291879329Impact of Methamphetamine Abuse: A Rare Case of Rapid Cerebral Aneurysm Growth with Review of LiteratureJames Fowler0Brian Fiani1Syed A. Quadri2Vladimir Cortez3Mudassir Frooqui4Atif Zafar5Fahad Shabbir Ahmed6Asad Ikram7Anirudh Ramachandran8Javed Siddiqi9Department of Neurosurgery, Desert Regional Medical Center, Palm Springs, CA, USADepartment of Neurosurgery, Desert Regional Medical Center, Palm Springs, CA, USADepartment of Neurosurgery, Desert Regional Medical Center, Palm Springs, CA, USADepartment of Neurosurgery, Desert Regional Medical Center, Palm Springs, CA, USADepartment of Neurology, University of New Mexico, Albuquerque, NM, USADepartment of Neurology, University of New Mexico, Albuquerque, NM, USADepartment of Pathology, Yale School of Medicine, New Haven, CT, USADepartment of Neurology, University of New Mexico, Albuquerque, NM, USACollege of Osteopathic Medicine of the Pacific, Western University of Health Sciences, Pomona, CA, USADepartment of Neurosurgery, Desert Regional Medical Center, Palm Springs, CA, USAMethamphetamine or “meth” is a sympathomimetic amine of the amphetamine-type substances (ATS) class with an extremely high potential for abuse. Illicitly abused neurostimulants like cocaine and meth predispose patients to the aneurysmal formation with reported rupture at a younger age and in much smaller sized aneurysms. However, very rapid growth of aneurysm within less than 2 weeks with methamphetamine abuse is very rarely observed or reported. In this report, we present a patient with repeated and recurrent meth abuse who demonstrated rapid growth of a pericallosal aneurysm over the period of less than two weeks. The pathophysiology of stroke related to meth and ATS abuse is multifactorial with hypertension, tachycardia, and vascular disease postulated as major mechanisms. The rapid growth of an aneurysm has a high risk of aneurysmal rupture and SAH, which is a neurosurgical emergency and therefore warrants careful consideration and close monitoring. This case confirms the dynamic temporal effects of methamphetamine use on intracranial vessels and this specific neurostimulants association to rapid aneurysmal formation. In light of vascular pathologies the possibility of drug-induced pseudoaneurysm should also be considered in young patients with history of meth abuse.http://dx.doi.org/10.1155/2018/1879329 |
| spellingShingle | James Fowler Brian Fiani Syed A. Quadri Vladimir Cortez Mudassir Frooqui Atif Zafar Fahad Shabbir Ahmed Asad Ikram Anirudh Ramachandran Javed Siddiqi Impact of Methamphetamine Abuse: A Rare Case of Rapid Cerebral Aneurysm Growth with Review of Literature Case Reports in Neurological Medicine |
| title | Impact of Methamphetamine Abuse: A Rare Case of Rapid Cerebral Aneurysm Growth with Review of Literature |
| title_full | Impact of Methamphetamine Abuse: A Rare Case of Rapid Cerebral Aneurysm Growth with Review of Literature |
| title_fullStr | Impact of Methamphetamine Abuse: A Rare Case of Rapid Cerebral Aneurysm Growth with Review of Literature |
| title_full_unstemmed | Impact of Methamphetamine Abuse: A Rare Case of Rapid Cerebral Aneurysm Growth with Review of Literature |
| title_short | Impact of Methamphetamine Abuse: A Rare Case of Rapid Cerebral Aneurysm Growth with Review of Literature |
| title_sort | impact of methamphetamine abuse a rare case of rapid cerebral aneurysm growth with review of literature |
| url | http://dx.doi.org/10.1155/2018/1879329 |
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