Local Injection versus Topical Microneedling of Platelet-Rich Plasma for Androgenetic Alopecia: A Systematic Review

Autologous platelet-rich plasma (PRP) has gained popularity for hair restoration due to its effectiveness and safety. PRP could be administered through direct local injections to the scalp or applied topically with the aid of microneedling therapy. This systematic review aims to elaborate on the eff...

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Bibliographic Details
Main Authors: Johannes Albert Biben, Ryan Reinhart, Karina Karina, Kuswan Ambar Pamungkas, Krista Ekaputri, Patricia Marcellina Sadikin
Format: Article
Language:English
Published: Thieme Medical Publishers, Inc. 2025-03-01
Series:Archives of Plastic Surgery
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Online Access:http://www.thieme-connect.de/DOI/DOI?10.1055/a-2510-5517
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Summary:Autologous platelet-rich plasma (PRP) has gained popularity for hair restoration due to its effectiveness and safety. PRP could be administered through direct local injections to the scalp or applied topically with the aid of microneedling therapy. This systematic review aims to elaborate on the effectiveness of PRP administered with syringe injection and topical PRP with microneedling combination for the treatment of androgenetic alopecia (AGA). A literature search was employed through PubMed, Cochrane Central Register of Controlled Trials, Embase, Web of Science, and Scopus. The database was searched using terms and keywords: “platelet-rich plasma” and “microneedling” and “androgenetic alopecia.” Inclusion criteria are human study, patients with AGA, studies that compare PRP with syringe injection and the combination of PRP and microneedling. Exclusion criteria are animal study, review, case reports, or studies on other form of alopecia.
ISSN:2234-6163
2234-6171