Comparison of Aqueous Depth Changes Following Cataract Surgery in Vitrectomized and Non-Vitrectomized Fellow Eyes

<b>Background/Objectives</b>: The role of the vitreous in the effective lens position (ELP) is controversial in patients undergoing phacovitrectomy. The aim of this study was to compare the change in aqueous depth (AD), a surrogate of the ELP, in non-vitrectomized and vitrectomized fello...

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Main Authors: Mercè Guarro, Laura Sararols, Elena López, Meritxell Vázquez, Sergi Ruiz, Marc Biarnés
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Diagnostics
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Online Access:https://www.mdpi.com/2075-4418/15/11/1429
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author Mercè Guarro
Laura Sararols
Elena López
Meritxell Vázquez
Sergi Ruiz
Marc Biarnés
author_facet Mercè Guarro
Laura Sararols
Elena López
Meritxell Vázquez
Sergi Ruiz
Marc Biarnés
author_sort Mercè Guarro
collection DOAJ
description <b>Background/Objectives</b>: The role of the vitreous in the effective lens position (ELP) is controversial in patients undergoing phacovitrectomy. The aim of this study was to compare the change in aqueous depth (AD), a surrogate of the ELP, in non-vitrectomized and vitrectomized fellow eyes. <b>Methods</b>: Post-hoc analysis of a prospective study conducted in OMIQ facilities (Barcelona, Spain) between 2021 and 2023. Patients with bilateral cataracts and a unilateral grade 2/3 epiretinal membrane underwent phacoemulsification in one eye and phacovitrectomy without endotamponade in the fellow eye. All eyes were implanted with an extended depth-of-focus intraocular lens after power calculation using the same biometer, technicians, formula, and surgeon. We compared the change in AD (mm and percentage) from baseline, and the role of vitrectomy without endotamponade on AD with a mixed-effects models. <b>Results</b>: We included 40 eyes (20 patients) with a mean age of 71.6 years, with 55% females. The mean change in AD was +1.51 (vitrectomized) and +1.42 mm (non-vitrectomized eyes), <i>p</i> = 0.33. The percent of change in AD was not different between groups (<i>p</i> ≥ 0.38) and phacovitrectomy had no effect on the change in AD on mixed-effects models (<i>p</i> > 0.10). <b>Conclusions</b>: The absence of the vitreous had a minimal influence on AD in these patients undergoing standard phacoemulsification or phacovitrectomy.
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spelling doaj-art-503be963328b480bbf4b4cec6f0ce52e2025-08-20T03:46:52ZengMDPI AGDiagnostics2075-44182025-06-011511142910.3390/diagnostics15111429Comparison of Aqueous Depth Changes Following Cataract Surgery in Vitrectomized and Non-Vitrectomized Fellow EyesMercè Guarro0Laura Sararols1Elena López2Meritxell Vázquez3Sergi Ruiz4Marc Biarnés5Oftalmologia Mèdica i Quirúrgica Research, c/Tamarit 39, 08905 Sabadell, Barcelona, SpainOftalmologia Mèdica i Quirúrgica Research, c/Tamarit 39, 08905 Sabadell, Barcelona, SpainOftalmologia Mèdica i Quirúrgica Research, c/Tamarit 39, 08905 Sabadell, Barcelona, SpainOftalmologia Mèdica i Quirúrgica Research, c/Tamarit 39, 08905 Sabadell, Barcelona, SpainOftalmologia Mèdica i Quirúrgica Research, c/Tamarit 39, 08905 Sabadell, Barcelona, SpainOftalmologia Mèdica i Quirúrgica Research, c/Tamarit 39, 08905 Sabadell, Barcelona, Spain<b>Background/Objectives</b>: The role of the vitreous in the effective lens position (ELP) is controversial in patients undergoing phacovitrectomy. The aim of this study was to compare the change in aqueous depth (AD), a surrogate of the ELP, in non-vitrectomized and vitrectomized fellow eyes. <b>Methods</b>: Post-hoc analysis of a prospective study conducted in OMIQ facilities (Barcelona, Spain) between 2021 and 2023. Patients with bilateral cataracts and a unilateral grade 2/3 epiretinal membrane underwent phacoemulsification in one eye and phacovitrectomy without endotamponade in the fellow eye. All eyes were implanted with an extended depth-of-focus intraocular lens after power calculation using the same biometer, technicians, formula, and surgeon. We compared the change in AD (mm and percentage) from baseline, and the role of vitrectomy without endotamponade on AD with a mixed-effects models. <b>Results</b>: We included 40 eyes (20 patients) with a mean age of 71.6 years, with 55% females. The mean change in AD was +1.51 (vitrectomized) and +1.42 mm (non-vitrectomized eyes), <i>p</i> = 0.33. The percent of change in AD was not different between groups (<i>p</i> ≥ 0.38) and phacovitrectomy had no effect on the change in AD on mixed-effects models (<i>p</i> > 0.10). <b>Conclusions</b>: The absence of the vitreous had a minimal influence on AD in these patients undergoing standard phacoemulsification or phacovitrectomy.https://www.mdpi.com/2075-4418/15/11/1429anterior chamber depthaqueous deptheffective lens positionphacoemulsificationphacovitrectomy
spellingShingle Mercè Guarro
Laura Sararols
Elena López
Meritxell Vázquez
Sergi Ruiz
Marc Biarnés
Comparison of Aqueous Depth Changes Following Cataract Surgery in Vitrectomized and Non-Vitrectomized Fellow Eyes
Diagnostics
anterior chamber depth
aqueous depth
effective lens position
phacoemulsification
phacovitrectomy
title Comparison of Aqueous Depth Changes Following Cataract Surgery in Vitrectomized and Non-Vitrectomized Fellow Eyes
title_full Comparison of Aqueous Depth Changes Following Cataract Surgery in Vitrectomized and Non-Vitrectomized Fellow Eyes
title_fullStr Comparison of Aqueous Depth Changes Following Cataract Surgery in Vitrectomized and Non-Vitrectomized Fellow Eyes
title_full_unstemmed Comparison of Aqueous Depth Changes Following Cataract Surgery in Vitrectomized and Non-Vitrectomized Fellow Eyes
title_short Comparison of Aqueous Depth Changes Following Cataract Surgery in Vitrectomized and Non-Vitrectomized Fellow Eyes
title_sort comparison of aqueous depth changes following cataract surgery in vitrectomized and non vitrectomized fellow eyes
topic anterior chamber depth
aqueous depth
effective lens position
phacoemulsification
phacovitrectomy
url https://www.mdpi.com/2075-4418/15/11/1429
work_keys_str_mv AT merceguarro comparisonofaqueousdepthchangesfollowingcataractsurgeryinvitrectomizedandnonvitrectomizedfelloweyes
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AT elenalopez comparisonofaqueousdepthchangesfollowingcataractsurgeryinvitrectomizedandnonvitrectomizedfelloweyes
AT meritxellvazquez comparisonofaqueousdepthchangesfollowingcataractsurgeryinvitrectomizedandnonvitrectomizedfelloweyes
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