Late Neonatal Sepsis with Acute Haematogenous Osteomyelitis Foci: Clinical Case
Background. The incidence of sepsis among newborns ranges from 1–12 to 38 per 1,000 live births in the world according to scientific literature [1, 2]. The clinical case demonstrates the features of the newborn organism sensitivity and the therapeutic and diagnostic process difficulties.Clinical cas...
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| Language: | Russian |
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Union of pediatricians of Russia
2020-09-01
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| Series: | Педиатрическая фармакология |
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| Online Access: | https://www.pedpharma.ru/jour/article/view/1875 |
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| author | Marietta V. Manucharyan Tatiana V. Turti Irina A. Belyaeva Tatiana E. Privalova Ludmila M. Makarova Marina A. Ovsyannikova |
| author_facet | Marietta V. Manucharyan Tatiana V. Turti Irina A. Belyaeva Tatiana E. Privalova Ludmila M. Makarova Marina A. Ovsyannikova |
| author_sort | Marietta V. Manucharyan |
| collection | DOAJ |
| description | Background. The incidence of sepsis among newborns ranges from 1–12 to 38 per 1,000 live births in the world according to scientific literature [1, 2]. The clinical case demonstrates the features of the newborn organism sensitivity and the therapeutic and diagnostic process difficulties.Clinical case description. The boy was born on the 37th week of gestation, 1st of twins, with body weight 3330 g, height 51 cm, APGAR score 8/9 points. He was on breastfeeding. His condition has deteriorated rapidly on the 9th day of life. The condition was severe due to intoxication syndrome, necrotising enterocolitis (NEC) manifestation, further development of systemic inflammatory response syndrome and multiple organ dysfunction syndrome. Severe pain syndrome and movement restraint in limbs have appeared on the 20th day of life. X-ray imaging: NEC signs, multiple osteomyelitis foci in the limbs.Conclusion. Modern adequate diagnosis and justified treatment tactics have led to positive outcome: child’s condition has improved, body weight has increased, pain syndrome has been managed, the volume of movements in the limbs has increased, inflammatory markers have stabilised. The child was discharged from hospital in satisfactory condition at the age of 2 months. |
| format | Article |
| id | doaj-art-502992dbd56540ba8b74ab8d303d5332 |
| institution | Kabale University |
| issn | 1727-5776 2500-3089 |
| language | Russian |
| publishDate | 2020-09-01 |
| publisher | Union of pediatricians of Russia |
| record_format | Article |
| series | Педиатрическая фармакология |
| spelling | doaj-art-502992dbd56540ba8b74ab8d303d53322025-08-20T03:59:21ZrusUnion of pediatricians of RussiaПедиатрическая фармакология1727-57762500-30892020-09-0117434535110.15690/pf.v17i4.21671725Late Neonatal Sepsis with Acute Haematogenous Osteomyelitis Foci: Clinical CaseMarietta V. Manucharyan0Tatiana V. Turti1Irina A. Belyaeva2Tatiana E. Privalova3Ludmila M. Makarova4Marina A. Ovsyannikova5Pirogov Russian National Research Medical UniversityPirogov Russian National Research Medical University; Research Institute of Pediatrics and Children’s Health in «Central Clinical Hospital of the Russian Academy of Sciences»; Research Institute for Healthcare and Medical Management of Moscow Health Department; G.N. Speransky Children’s Municipal Clinical Hospital № 9Pirogov Russian National Research Medical University; Research Institute of Pediatrics and Children’s Health in «Central Clinical Hospital of the Russian Academy of Sciences»; Morozov Children’s City Clinical HospitalPirogov Russian National Research Medical University; Research Institute of Pediatrics and Children’s Health in «Central Clinical Hospital of the Russian Academy of Sciences»G.N. Speransky Children’s Municipal Clinical Hospital № 9G.N. Speransky Children’s Municipal Clinical Hospital № 9Background. The incidence of sepsis among newborns ranges from 1–12 to 38 per 1,000 live births in the world according to scientific literature [1, 2]. The clinical case demonstrates the features of the newborn organism sensitivity and the therapeutic and diagnostic process difficulties.Clinical case description. The boy was born on the 37th week of gestation, 1st of twins, with body weight 3330 g, height 51 cm, APGAR score 8/9 points. He was on breastfeeding. His condition has deteriorated rapidly on the 9th day of life. The condition was severe due to intoxication syndrome, necrotising enterocolitis (NEC) manifestation, further development of systemic inflammatory response syndrome and multiple organ dysfunction syndrome. Severe pain syndrome and movement restraint in limbs have appeared on the 20th day of life. X-ray imaging: NEC signs, multiple osteomyelitis foci in the limbs.Conclusion. Modern adequate diagnosis and justified treatment tactics have led to positive outcome: child’s condition has improved, body weight has increased, pain syndrome has been managed, the volume of movements in the limbs has increased, inflammatory markers have stabilised. The child was discharged from hospital in satisfactory condition at the age of 2 months.https://www.pedpharma.ru/jour/article/view/1875late neonatal sepsisnecrotising enterocolitishaematogenous osteomyelitisnewborninflammatory markersc-reactive proteinprocalcitoninclinical case |
| spellingShingle | Marietta V. Manucharyan Tatiana V. Turti Irina A. Belyaeva Tatiana E. Privalova Ludmila M. Makarova Marina A. Ovsyannikova Late Neonatal Sepsis with Acute Haematogenous Osteomyelitis Foci: Clinical Case Педиатрическая фармакология late neonatal sepsis necrotising enterocolitis haematogenous osteomyelitis newborn inflammatory markers c-reactive protein procalcitonin clinical case |
| title | Late Neonatal Sepsis with Acute Haematogenous Osteomyelitis Foci: Clinical Case |
| title_full | Late Neonatal Sepsis with Acute Haematogenous Osteomyelitis Foci: Clinical Case |
| title_fullStr | Late Neonatal Sepsis with Acute Haematogenous Osteomyelitis Foci: Clinical Case |
| title_full_unstemmed | Late Neonatal Sepsis with Acute Haematogenous Osteomyelitis Foci: Clinical Case |
| title_short | Late Neonatal Sepsis with Acute Haematogenous Osteomyelitis Foci: Clinical Case |
| title_sort | late neonatal sepsis with acute haematogenous osteomyelitis foci clinical case |
| topic | late neonatal sepsis necrotising enterocolitis haematogenous osteomyelitis newborn inflammatory markers c-reactive protein procalcitonin clinical case |
| url | https://www.pedpharma.ru/jour/article/view/1875 |
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