Lithium Induces Oxidative Stress, Apoptotic Cell Death, and G2/M Phase Cell Cycle Arrest in A549 Lung Cancer Cells

Lithium Induces Oxidative Stress, Apoptotic Cell Death, and G2/M Phase Cell Cycle Arrest in A549 Lung Cancer Cells

Lithium has been identified more than six decades ago as a preferred treatment option for manic depression. Due to its affordability, stability, minimal side effects, and immunomodulatory effects, recent studies on lithium have focused on its potential anticancer properties and possible mechanisms o...

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Bibliographic Details
Main Authors: Pearl Ramushu, Dikgale D. Mangoakoane, Raymond T. Makola, Thabe M. Matsebatlela
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Molecules
Subjects:
lithium chloride
lung cancer
oxidative stress
apoptosis
cell cycle arrest
Online Access:https://www.mdpi.com/1420-3049/30/8/1797
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