Respiratory Admissions Linked to Air Pollution in a Medium Sized City of the UK: A Case-crossover Study
Abstract This study, from the Tayside Pollution Research Programme (TPRP), aims to investigate the effects of air pollution on respiratory hospital admissions in adults and children < 16 y of age, over a 14-year period, in Dundee, Scotland (population circa 148,270). We conducted a case-crossover...
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| Format: | Article |
| Language: | English |
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Springer
2023-06-01
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| Series: | Aerosol and Air Quality Research |
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| Online Access: | https://doi.org/10.4209/aaqr.230062 |
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| author | Catherine A. Fitton Bianca Cox Munro Stewart James Chalmers Jill J. F. Belch |
| author_facet | Catherine A. Fitton Bianca Cox Munro Stewart James Chalmers Jill J. F. Belch |
| author_sort | Catherine A. Fitton |
| collection | DOAJ |
| description | Abstract This study, from the Tayside Pollution Research Programme (TPRP), aims to investigate the effects of air pollution on respiratory hospital admissions in adults and children < 16 y of age, over a 14-year period, in Dundee, Scotland (population circa 148,270). We conducted a case-crossover study using routinely collected healthcare records from Ninewells Hospital, Dundee, Scotland from 2004 to 2017. Respiratory hospitalisation events were linked to daily nitric oxide gases (NOx, NO2, NO) extracted from publicly available data over this period. We used distributed lag models to allow for delayed effects of air pollutants up to 14 days. A total of 34,192 hospital admissions for a respiratory condition were included in this study (children = 9,501; adults = 24,691). Respiratory admissions in children were significantly associated with cumulative 14-day exposure to NOx (RR for a 10 µg m−3 increase in concentration 1.020; 95% confidence interval 1.010–1.031), NO2 (RR 1.086; 95% CI 1.036–1.139) and NO (RR 1.033; 95% CI 1.016–1.052). Similar estimates were observed for acute respiratory infection categories in children. Effects appeared to be somewhat delayed, with the largest estimates mostly observed around lag 6. No significant association was seen for respiratory admissions in adults. This study shows that both NO and NO2 are associated with increased respiratory hospital admissions in children < 16 y of age, and that much more should be done to improve and enforce the established legal NOx pollution limits in cities for the sake of our children’s health. |
| format | Article |
| id | doaj-art-500d621ef9334355b2a8cd2050dbbbb7 |
| institution | Kabale University |
| issn | 1680-8584 2071-1409 |
| language | English |
| publishDate | 2023-06-01 |
| publisher | Springer |
| record_format | Article |
| series | Aerosol and Air Quality Research |
| spelling | doaj-art-500d621ef9334355b2a8cd2050dbbbb72025-02-09T12:23:03ZengSpringerAerosol and Air Quality Research1680-85842071-14092023-06-0123811010.4209/aaqr.230062Respiratory Admissions Linked to Air Pollution in a Medium Sized City of the UK: A Case-crossover StudyCatherine A. Fitton0Bianca Cox1Munro Stewart2James Chalmers3Jill J. F. Belch4University of Dundee NHS Tayside, Ninewells HospitalVITO Health, Flemish Institute for Technological Research (VITO)Nethergate Medical CentreUniversity of Dundee NHS Tayside, Ninewells HospitalUniversity of Dundee NHS Tayside, Ninewells HospitalAbstract This study, from the Tayside Pollution Research Programme (TPRP), aims to investigate the effects of air pollution on respiratory hospital admissions in adults and children < 16 y of age, over a 14-year period, in Dundee, Scotland (population circa 148,270). We conducted a case-crossover study using routinely collected healthcare records from Ninewells Hospital, Dundee, Scotland from 2004 to 2017. Respiratory hospitalisation events were linked to daily nitric oxide gases (NOx, NO2, NO) extracted from publicly available data over this period. We used distributed lag models to allow for delayed effects of air pollutants up to 14 days. A total of 34,192 hospital admissions for a respiratory condition were included in this study (children = 9,501; adults = 24,691). Respiratory admissions in children were significantly associated with cumulative 14-day exposure to NOx (RR for a 10 µg m−3 increase in concentration 1.020; 95% confidence interval 1.010–1.031), NO2 (RR 1.086; 95% CI 1.036–1.139) and NO (RR 1.033; 95% CI 1.016–1.052). Similar estimates were observed for acute respiratory infection categories in children. Effects appeared to be somewhat delayed, with the largest estimates mostly observed around lag 6. No significant association was seen for respiratory admissions in adults. This study shows that both NO and NO2 are associated with increased respiratory hospital admissions in children < 16 y of age, and that much more should be done to improve and enforce the established legal NOx pollution limits in cities for the sake of our children’s health.https://doi.org/10.4209/aaqr.230062NOxPollutionRespiratory diseaseChildrenNitrogen oxide |
| spellingShingle | Catherine A. Fitton Bianca Cox Munro Stewart James Chalmers Jill J. F. Belch Respiratory Admissions Linked to Air Pollution in a Medium Sized City of the UK: A Case-crossover Study Aerosol and Air Quality Research NOx Pollution Respiratory disease Children Nitrogen oxide |
| title | Respiratory Admissions Linked to Air Pollution in a Medium Sized City of the UK: A Case-crossover Study |
| title_full | Respiratory Admissions Linked to Air Pollution in a Medium Sized City of the UK: A Case-crossover Study |
| title_fullStr | Respiratory Admissions Linked to Air Pollution in a Medium Sized City of the UK: A Case-crossover Study |
| title_full_unstemmed | Respiratory Admissions Linked to Air Pollution in a Medium Sized City of the UK: A Case-crossover Study |
| title_short | Respiratory Admissions Linked to Air Pollution in a Medium Sized City of the UK: A Case-crossover Study |
| title_sort | respiratory admissions linked to air pollution in a medium sized city of the uk a case crossover study |
| topic | NOx Pollution Respiratory disease Children Nitrogen oxide |
| url | https://doi.org/10.4209/aaqr.230062 |
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