Effects of physical activity on visual outcomes among type 2 diabetes patients: protocol for a scoping review of randomized controlled trials

Abstract Background Type 2 diabetes mellitus remains a major global health concern, affecting millions of patients worldwide resulting in complications, including diabetic retinopathy, one of the leading causes of blindness. Despite the existence and popularity of lifestyle interventions like physic...

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Main Authors: Ebenezer Oduro Antiri, Thomas Hormenu, Stephen Ocansey, Edward Wilson Ansah
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Systematic Reviews
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Online Access:https://doi.org/10.1186/s13643-025-02887-z
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author Ebenezer Oduro Antiri
Thomas Hormenu
Stephen Ocansey
Edward Wilson Ansah
author_facet Ebenezer Oduro Antiri
Thomas Hormenu
Stephen Ocansey
Edward Wilson Ansah
author_sort Ebenezer Oduro Antiri
collection DOAJ
description Abstract Background Type 2 diabetes mellitus remains a major global health concern, affecting millions of patients worldwide resulting in complications, including diabetic retinopathy, one of the leading causes of blindness. Despite the existence and popularity of lifestyle interventions like physical activity in managing diabetes, there is limited evidence exploring higher evidence like randomized controlled trials (RCTs) that have investigated these interventions and their relation with visual outcomes in people with type 2 diabetes mellitus. This protocol outlines a scoping review method that aims to explore literature that used RCTs to study the effects of physical activity interventions on visual outcomes in persons with T2DM. Methods This scoping review protocol will be guided by the Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR) and the JBI framework for conducting scoping reviews. Thorough search strategies will be designed across databases, including MEDLINE, Cochrane CENTRAL, and JSTOR. Searches will be conducted in clinical registries to supplement the search in the above databases. The studies will be included in this review if they are RCTs conducted among individuals with T2DM and measured the effects of physical activity on visual outcomes. Because this is a scoping review, all relevant studies will be included without a risk-of-bias assessment. The data will be extracted, charted, and analyzed to give an overview of the interrelations of the variables in the literature. The review is expected to be completed by end of June 2025. Discussion Despite the debilitating effects of diabetes, including its telling effects on the eye and vision, the thoroughness of the evidence concerning physical activity clinical trials, and how they affect visual outcomes in people with T2DM, is yet to be assessed. While acknowledging potential limitations like language limits and publication bias, this review seeks to provide valuable insight regarding the contribution of physical activity in enhancing visual health among T2DM patients. This review aims to synthesize evidence from RCTs to contribute to broader discussions on clinical care and policy-making and to encourage future research efforts. Systematic review registration The scoping review protocol has been registered on the Open Science Framework ( https://osf.io/856yb ).
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spelling doaj-art-500ce2a4a0ec4c3598e7d062dccfdde52025-08-20T03:04:10ZengBMCSystematic Reviews2046-40532025-07-0114111010.1186/s13643-025-02887-zEffects of physical activity on visual outcomes among type 2 diabetes patients: protocol for a scoping review of randomized controlled trialsEbenezer Oduro Antiri0Thomas Hormenu1Stephen Ocansey2Edward Wilson Ansah3Department of Health, Physical Education and Recreation, University of Cape CoastDepartment of Health, Physical Education and Recreation, University of Cape CoastSchool of Optometry and Vision Science, University of Cape CoastDepartment of Health, Physical Education and Recreation, University of Cape CoastAbstract Background Type 2 diabetes mellitus remains a major global health concern, affecting millions of patients worldwide resulting in complications, including diabetic retinopathy, one of the leading causes of blindness. Despite the existence and popularity of lifestyle interventions like physical activity in managing diabetes, there is limited evidence exploring higher evidence like randomized controlled trials (RCTs) that have investigated these interventions and their relation with visual outcomes in people with type 2 diabetes mellitus. This protocol outlines a scoping review method that aims to explore literature that used RCTs to study the effects of physical activity interventions on visual outcomes in persons with T2DM. Methods This scoping review protocol will be guided by the Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR) and the JBI framework for conducting scoping reviews. Thorough search strategies will be designed across databases, including MEDLINE, Cochrane CENTRAL, and JSTOR. Searches will be conducted in clinical registries to supplement the search in the above databases. The studies will be included in this review if they are RCTs conducted among individuals with T2DM and measured the effects of physical activity on visual outcomes. Because this is a scoping review, all relevant studies will be included without a risk-of-bias assessment. The data will be extracted, charted, and analyzed to give an overview of the interrelations of the variables in the literature. The review is expected to be completed by end of June 2025. Discussion Despite the debilitating effects of diabetes, including its telling effects on the eye and vision, the thoroughness of the evidence concerning physical activity clinical trials, and how they affect visual outcomes in people with T2DM, is yet to be assessed. While acknowledging potential limitations like language limits and publication bias, this review seeks to provide valuable insight regarding the contribution of physical activity in enhancing visual health among T2DM patients. This review aims to synthesize evidence from RCTs to contribute to broader discussions on clinical care and policy-making and to encourage future research efforts. Systematic review registration The scoping review protocol has been registered on the Open Science Framework ( https://osf.io/856yb ).https://doi.org/10.1186/s13643-025-02887-zPhysical activityType 2 diabetes mellitusVisual outcomesRandomized controlled trialsDiabetic retinopathy
spellingShingle Ebenezer Oduro Antiri
Thomas Hormenu
Stephen Ocansey
Edward Wilson Ansah
Effects of physical activity on visual outcomes among type 2 diabetes patients: protocol for a scoping review of randomized controlled trials
Systematic Reviews
Physical activity
Type 2 diabetes mellitus
Visual outcomes
Randomized controlled trials
Diabetic retinopathy
title Effects of physical activity on visual outcomes among type 2 diabetes patients: protocol for a scoping review of randomized controlled trials
title_full Effects of physical activity on visual outcomes among type 2 diabetes patients: protocol for a scoping review of randomized controlled trials
title_fullStr Effects of physical activity on visual outcomes among type 2 diabetes patients: protocol for a scoping review of randomized controlled trials
title_full_unstemmed Effects of physical activity on visual outcomes among type 2 diabetes patients: protocol for a scoping review of randomized controlled trials
title_short Effects of physical activity on visual outcomes among type 2 diabetes patients: protocol for a scoping review of randomized controlled trials
title_sort effects of physical activity on visual outcomes among type 2 diabetes patients protocol for a scoping review of randomized controlled trials
topic Physical activity
Type 2 diabetes mellitus
Visual outcomes
Randomized controlled trials
Diabetic retinopathy
url https://doi.org/10.1186/s13643-025-02887-z
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