1,8-Cineole inhibits platelet-leukocyte aggregate formation by reducing P-selectin expression

1,8-Cineole inhibits platelet-leukocyte aggregate formation by reducing P-selectin expression

IntroductionPlatelets, traditionally recognized for their role in hemostasis, have increasingly been implicated in cancer progression, including head and neck squamous cell carcinoma (HNSCC). Beyond releasing growth factors and chemokines, platelets modulate leukocyte-mediated proinflammatory respon...

Full description

Saved in:

Bibliographic Details
Main Authors:	Julie Petry, Han Mai, Maria Shoykhet, Ali Bashiri Dezfouli, Barbara Wollenberg
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-06-01
Series:	Frontiers in Pharmacology
Subjects:	1,8-cineole platelets platelet-leukocyte aggregates anti-platelet drugs head and neck squamous cell carcinoma
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2025.1546157/full
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Correction: 1,8-Cineole inhibits platelet-leukocyte aggregate formation by reducing P-selectin expression
by: Julie Petry, et al.
Published: (2025-07-01)

Platelet-leukocyte interactions: immunoregulatory role and pathophysiological relevance
by: O. V. Pavlov, et al.
Published: (2022-11-01)

Research progress on the relationship between platelets and periodontitis
by: ZHANG Yitao, CHENG Rui, MI Zhongqian, REN Xiuyun
Published: (2024-12-01)

Prostate Tissue-Induced Platelet Activation and Platelet–Neutrophil Aggregation Following Transurethral Resection of the Prostate Surgery: An In Vitro Study
by: Po-An Lin, et al.
Published: (2025-04-01)

Flow cytometry for evaluating platelet immunophenotyping and function in patients with thrombocytopenia
by: Chih-Lung Shen, et al.
Published: (2022-01-01)

THE SIZE OF PLATELET-LEUKOCYTE AGGREGATES IN PATIENTS WITH VARIOUS DEGREE OF CORONARY ATHEROSCLEROSIS
by: Irina V. Kologrivova, et al.
Published: (2019-08-01)

Platelet aggregation study: Valuable aid to diagnose dysfibrinogenemia.
by: Abhishek Purohit, et al.
Published: (2014-08-01)

Head and neck squamous cell carcinoma-derived extracellular vesicles mediate Ca²⁺-dependent platelet activation and aggregation through tissue factor
by: Tobias Weiser, et al.
Published: (2025-05-01)

The role of platelets in inflammation and immunity
by: S. P. Sviridova, et al.
Published: (2018-09-01)

Сellular composition of platelet-rich plasma evaluation in order to optimize its use in macular hole surgery. Part 1
by: A.Yu. Kleymenov, et al.
Published: (2023-06-01)

THE EFFECTIVENESS OF PAPAYA LEAF EXTRACT (CARICA PAPAYA L.) AS AN ANTIAGGREGATION AGENT ON PLATELET COUNT AND PLATELET AGGREGATION: IN VITRO STUDY
by: Ganjar Noviar, et al.
Published: (2025-07-01)

Intraarticular leukocyte-poor platelet-rich plasma injection is more effective than intraarticular hyaluronic acid injection in the treatment of knee osteoarthritis: a systematic review and meta-analysis of 12 randomized controlled trials
by: Yu-Ning Peng, et al.
Published: (2025-03-01)

NebulaPlate: a droplet microfluidic platform to analyze platelet aggregation
by: Zheyi Jiang, et al.
Published: (2025-03-01)

Gut microbial communities in chronic rhinosinusitis patients in response to 1,8-Cineol treatment
by: Simon Graspeuntner, et al.
Published: (2025-01-01)

BETA-ADRENOBLOCKERS AND PLATELET AGGREGATION. CARVEDILOL
by: A. N. Zakirova, et al.
Published: (2016-01-01)

Aggregation activity of blood formed elements in patients with type 1 and type 2 diabetes mellitus
by: Boris Il'ich Kuznik, et al.
Published: (2012-06-01)

Indicators of ADP-induced platelet aggregation in patients with hypertension complicated by ischemic hemisphere stroke
by: V. V. Syvolap, et al.
Published: (2017-10-01)

Influence of rose bengal on platelet aggregation activity
by: N. N. Petrishchev, et al.
Published: (2022-05-01)

PLATELET TURNOVER AND ATHEROTHROMBOSIS
by: A. V. MAZUROV
Published: (2017-12-01)

An isolated case of pseudothrombocytopenia due to platelet satellitism with the review of literature
by: Meenakshi Suri
Published: (2024-01-01)

Effect of blood pressure normalization (reaching the target level) on epinephrine-induced platelet aggregation changes in patients with hypertension
by: V. V. Syvolap, et al.
Published: (2017-06-01)

Adrenalin-induced platelet aggregation in essential hypertensive patients in the acute phase of hemispheric ischaemic stroke: LTA results
by: S. P. Zhemanyuk, et al.
Published: (2017-11-01)

Leukocyte platelet-rich fibrin in endodontic microsurgery: a report of 2 cases
by: Mariana Domingos Pires, et al.
Published: (2022-05-01)

A review of natural compounds to regulate platelet aggregation: molecular mechanism and research advance
by: Yi Hou, et al.
Published: (2025-06-01)

Features of ADP-induced platelet aggregation in patients with community-acquired pneumonia 3-d group and its changes during treatment
by: V. V. Syvolap, et al.
Published: (2016-06-01)

Microscopic evaluation of the effect of low-level laser therapy on platelet-rich fibrin: An in vitro study
by: Sruthi Kallayil Suresh, et al.
Published: (2024-09-01)

Over-activation and dysfunction of platelet-NK cell aggregates in HIV-infected individuals
by: Meiju Deng, et al.
Published: (2025-05-01)

Evaluating platelet concentrates by platelet indices, thromboelastography, and flow cytometry
by: Tapasyapreeti Mukhopadhyay, et al.
Published: (2024-12-01)

Disorders of the aggregation function of platelets against the background of a deficiency of certain vitamins and microelements in children
by: O. B. Gordeeva, et al.
Published: (2023-10-01)

Differential influence of 1,8-Cineol on distinct hypoxia-related immune alterations in human monocytes
by: Nele Jagodzinski, et al.
Published: (2025-04-01)

Modulatory Efficiency of Vitamin C (Ascorbic Acid) on Collagen-Induced Platelet Aggregation and Dysfunction
by: Osah Martins Onwuka, et al.
Published: (2025-01-01)

Establishment and capacity analysis of the platelet donor database with HPA and HLA genotype in Nanjing
by: LIU Taixiang, et al.
Published: (2024-10-01)

Thrombocyte aggregation activity in the conditions of intensive light deprivation
by: V. F. Kirichuk, et al.
Published: (2020-07-01)

Fucosylated Glycosaminoglycan Oligosaccharide HS14, Derived from Sea Cucumbers, Is a Novel Inhibitor of Platelet Toll-like Receptor 2
by: Huifang Sun, et al.
Published: (2025-03-01)

Platelets and hemostasis
by: M. A. Panteleev, et al.
Published: (2014-09-01)

Nanodrug-based modulation of platelet–leukocyte interactions in ovarian cancer: a new frontier in targeted therapy
by: Jalal Naghinezhad, et al.
Published: (2025-08-01)

Proinflammatory biomarkers and platelet aggregation activity in patients with coronary artery disease
by: O. A. Trubacheva, et al.
Published: (2024-01-01)

POTENTIAL OF ALOE VERA GEL AS AN ALTERNATIVE INDUCTOR IN PLATELET AGGREGATION TEST
by: Gela Setya Ayu Putri, et al.
Published: (2023-06-01)

Changes of platelets activity in patient swith COPD and concomitant arterial hypertension under the influence of L-arginine.
by: О. М. Kovalenko
Published: (2018-05-01)

Platelet aggregation, dyslipoproteinemia and polyunsaturated fatty acids
by: E. I. Sokolov, et al.
Published: (2006-10-01)