The Effect of Development in Respiratory Sensory Gating Measured by Electrocortical Activations

The perception of respiratory sensations can be of significant importance to individuals for survival and greatly impact quality of life. Respiratory sensory gating, similar to somatosensory gating with exteroceptive stimuli, is indicative of brain cortices filtering out repetitive respiratory stimu...

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Main Authors: Pei-Ying S. Chan, Chia-Hsiung Cheng, Andreas von Leupoldt
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Neural Plasticity
Online Access:http://dx.doi.org/10.1155/2015/389142
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author Pei-Ying S. Chan
Chia-Hsiung Cheng
Andreas von Leupoldt
author_facet Pei-Ying S. Chan
Chia-Hsiung Cheng
Andreas von Leupoldt
author_sort Pei-Ying S. Chan
collection DOAJ
description The perception of respiratory sensations can be of significant importance to individuals for survival and greatly impact quality of life. Respiratory sensory gating, similar to somatosensory gating with exteroceptive stimuli, is indicative of brain cortices filtering out repetitive respiratory stimuli and has been investigated in adults with and without diseases. Respiratory gating can be tested with the respiratory-related evoked potential (RREP) method in the electroencephalogram with a paired inspiratory occlusion paradigm. Here, the RREP N1 component elicited by the second stimulus (S2) shows reduced amplitudes compared to the RREP N1 component elicited by the first stimulus (S1). However, little is known regarding the effect of development on respiratory sensory gating. The present study examined respiratory sensory gating in 22 typically developed school-aged children and 22 healthy adults. Paired inspiratory occlusions of 150-ms each with an inter-stimulus-interval of 500-ms were delivered randomly every 2–4 breaths during recording. The main results showed a significantly larger RREP N1 S2/S1 ratio in the children group than in the adult group. In addition, children compared to adults demonstrated significantly smaller N1 peak amplitudes in response to S1. Our results suggest that school-aged children, compared to adults, display reduced respiratory sensory gating.
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spelling doaj-art-4ffc7dd971b74d558495e7197754c01d2025-08-20T02:05:37ZengWileyNeural Plasticity2090-59041687-54432015-01-01201510.1155/2015/389142389142The Effect of Development in Respiratory Sensory Gating Measured by Electrocortical ActivationsPei-Ying S. Chan0Chia-Hsiung Cheng1Andreas von Leupoldt2Department of Occupational Therapy, College of Medicine, Chang Gung University, No. 259, Wen-Hwa 1st Road, Taoyuan 333, TaiwanDepartment of Occupational Therapy, College of Medicine, Chang Gung University, No. 259, Wen-Hwa 1st Road, Taoyuan 333, TaiwanResearch Group on Health Psychology, University of Leuven, Tiensestraat 102, 3000 Leuven, BelgiumThe perception of respiratory sensations can be of significant importance to individuals for survival and greatly impact quality of life. Respiratory sensory gating, similar to somatosensory gating with exteroceptive stimuli, is indicative of brain cortices filtering out repetitive respiratory stimuli and has been investigated in adults with and without diseases. Respiratory gating can be tested with the respiratory-related evoked potential (RREP) method in the electroencephalogram with a paired inspiratory occlusion paradigm. Here, the RREP N1 component elicited by the second stimulus (S2) shows reduced amplitudes compared to the RREP N1 component elicited by the first stimulus (S1). However, little is known regarding the effect of development on respiratory sensory gating. The present study examined respiratory sensory gating in 22 typically developed school-aged children and 22 healthy adults. Paired inspiratory occlusions of 150-ms each with an inter-stimulus-interval of 500-ms were delivered randomly every 2–4 breaths during recording. The main results showed a significantly larger RREP N1 S2/S1 ratio in the children group than in the adult group. In addition, children compared to adults demonstrated significantly smaller N1 peak amplitudes in response to S1. Our results suggest that school-aged children, compared to adults, display reduced respiratory sensory gating.http://dx.doi.org/10.1155/2015/389142
spellingShingle Pei-Ying S. Chan
Chia-Hsiung Cheng
Andreas von Leupoldt
The Effect of Development in Respiratory Sensory Gating Measured by Electrocortical Activations
Neural Plasticity
title The Effect of Development in Respiratory Sensory Gating Measured by Electrocortical Activations
title_full The Effect of Development in Respiratory Sensory Gating Measured by Electrocortical Activations
title_fullStr The Effect of Development in Respiratory Sensory Gating Measured by Electrocortical Activations
title_full_unstemmed The Effect of Development in Respiratory Sensory Gating Measured by Electrocortical Activations
title_short The Effect of Development in Respiratory Sensory Gating Measured by Electrocortical Activations
title_sort effect of development in respiratory sensory gating measured by electrocortical activations
url http://dx.doi.org/10.1155/2015/389142
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