Mineralization of the Peritoneum — a New Target in the Treatment of Peritoneal Carcinomatosis
Introduction. This article presents data on the manifestations of changes in the microenvironment of the peritoneal cavity in patients with carcinomatosis, expressed by the mineralization of the peritoneum, which in turn leads to functional changes in drainage of the peritoneal cavity.Materials and...
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| Language: | English |
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Bashkir State Medical University
2019-03-01
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| Series: | Креативная хирургия и онкология |
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| Online Access: | https://www.surgonco.ru/jour/article/view/347 |
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| author | Sh. Kh. Gantsev V. M. Moiseenko K. Sh. Gantsev S. V. Solomenny Sh. R. Kzyrgalin V. A. Dokichev F. V. Moiseenko R. S. Minigazimov |
| author_facet | Sh. Kh. Gantsev V. M. Moiseenko K. Sh. Gantsev S. V. Solomenny Sh. R. Kzyrgalin V. A. Dokichev F. V. Moiseenko R. S. Minigazimov |
| author_sort | Sh. Kh. Gantsev |
| collection | DOAJ |
| description | Introduction. This article presents data on the manifestations of changes in the microenvironment of the peritoneal cavity in patients with carcinomatosis, expressed by the mineralization of the peritoneum, which in turn leads to functional changes in drainage of the peritoneal cavity.Materials and methods. We examined autopsy tissue of the peritoneum with symptoms of carcinomatosis and intact peritoneum using comparative scanning electron microscopy.Results and discussion. The study of the ultrastructure of peritoneum in patients with PC, revealed the phenomenon of SLL mineralization. The resulting elemental composition profile showed a high content of Ca, P, Na.Conclusions. 1. Carcinomatosis is not a local, but rather a systemic process. Determining the role of mineralization in carcinomatosis is of fundamental importance in carcinogenesis. 2. The serous membranes mineralization in patients with carcinomatosis can become a new treatment target, the impact on which may increase life expectancy and improve the quality of life. 3. The serous membranes demineralization can serve as a part of a combination treatment that includes the subsequent endolymphatic anti-tumour drug therapy. |
| format | Article |
| id | doaj-art-4fe78d4b9bf24ccaad3e2747bb4f89cf |
| institution | DOAJ |
| issn | 2076-3093 2307-0501 |
| language | English |
| publishDate | 2019-03-01 |
| publisher | Bashkir State Medical University |
| record_format | Article |
| series | Креативная хирургия и онкология |
| spelling | doaj-art-4fe78d4b9bf24ccaad3e2747bb4f89cf2025-08-20T03:19:20ZengBashkir State Medical UniversityКреативная хирургия и онкология2076-30932307-05012019-03-018427928410.24060/2076-3093-2018-8-4-279-284298Mineralization of the Peritoneum — a New Target in the Treatment of Peritoneal CarcinomatosisSh. Kh. Gantsev0V. M. Moiseenko1K. Sh. Gantsev2S. V. Solomenny3Sh. R. Kzyrgalin4V. A. Dokichev5F. V. Moiseenko6R. S. Minigazimov7Bashkir State Medical UniversitySt. Petersburg Clinical Research and Practical Center for Specialized Types of Medical Care (Oncologic)Bashkir State Medical UniversityCity Clinical Hospital № 13Bashkir State Medical UniversityUfa State Aviation Technical UniversitySt. Petersburg Clinical Research and Practical Center for Specialized Types of Medical Care (Oncologic)Bashkir State Medical UniversityIntroduction. This article presents data on the manifestations of changes in the microenvironment of the peritoneal cavity in patients with carcinomatosis, expressed by the mineralization of the peritoneum, which in turn leads to functional changes in drainage of the peritoneal cavity.Materials and methods. We examined autopsy tissue of the peritoneum with symptoms of carcinomatosis and intact peritoneum using comparative scanning electron microscopy.Results and discussion. The study of the ultrastructure of peritoneum in patients with PC, revealed the phenomenon of SLL mineralization. The resulting elemental composition profile showed a high content of Ca, P, Na.Conclusions. 1. Carcinomatosis is not a local, but rather a systemic process. Determining the role of mineralization in carcinomatosis is of fundamental importance in carcinogenesis. 2. The serous membranes mineralization in patients with carcinomatosis can become a new treatment target, the impact on which may increase life expectancy and improve the quality of life. 3. The serous membranes demineralization can serve as a part of a combination treatment that includes the subsequent endolymphatic anti-tumour drug therapy.https://www.surgonco.ru/jour/article/view/347peritoneumcarcinomatosismineralizationcalcinosisserous lymphatic hatchdemineralization |
| spellingShingle | Sh. Kh. Gantsev V. M. Moiseenko K. Sh. Gantsev S. V. Solomenny Sh. R. Kzyrgalin V. A. Dokichev F. V. Moiseenko R. S. Minigazimov Mineralization of the Peritoneum — a New Target in the Treatment of Peritoneal Carcinomatosis Креативная хирургия и онкология peritoneum carcinomatosis mineralization calcinosis serous lymphatic hatch demineralization |
| title | Mineralization of the Peritoneum — a New Target in the Treatment of Peritoneal Carcinomatosis |
| title_full | Mineralization of the Peritoneum — a New Target in the Treatment of Peritoneal Carcinomatosis |
| title_fullStr | Mineralization of the Peritoneum — a New Target in the Treatment of Peritoneal Carcinomatosis |
| title_full_unstemmed | Mineralization of the Peritoneum — a New Target in the Treatment of Peritoneal Carcinomatosis |
| title_short | Mineralization of the Peritoneum — a New Target in the Treatment of Peritoneal Carcinomatosis |
| title_sort | mineralization of the peritoneum a new target in the treatment of peritoneal carcinomatosis |
| topic | peritoneum carcinomatosis mineralization calcinosis serous lymphatic hatch demineralization |
| url | https://www.surgonco.ru/jour/article/view/347 |
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