Comparative Genomics of <i>Bifidobacterium animalis</i> subsp. <i>lactis</i> Reveals Strain-Level Hyperdiversity, Carbohydrate Metabolism Adaptations, and CRISPR-Mediated Phage Immunity

Comparative Genomics of <i>Bifidobacterium animalis</i> subsp. <i>lactis</i> Reveals Strain-Level Hyperdiversity, Carbohydrate Metabolism Adaptations, and CRISPR-Mediated Phage Immunity

Several strains of <i>Bifidobacterium animalis</i> subsp. <i>lactis</i> are blockbusters of commercial dietary supplement cocktails, widely recognized for their probiotic properties and found in various ecological niches. The present study aimed to perform an in-depth compara...

Full description

Saved in:

Bibliographic Details
Main Authors:	Ozge Can, Ismail Gumustop, Ibrahim Genel, Hulya Unver, Enes Dertli, Ibrahim Cagri Kurt, Fatih Ortakci
Format:	Article
Language:	English
Published:	MDPI AG 2025-03-01
Series:	Fermentation
Subjects:	<i>Bifidobacterium lactis</i> comparative genomics CRISPR CAZYME
Online Access:	https://www.mdpi.com/2311-5637/11/4/179
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Development of Alginate Composite Microparticles for Encapsulation of <i>Bifidobacterium animalis</i> subsp. <i>lactis</i>
by: Marko Vinceković, et al.
Published: (2024-11-01)

Development of a Strain-Specific Detection and Quantification Method for <i>Bifidobacterium animalis</i> subsp. <i>lactis</i> HN019 Using WGS-SNP Analysis and qPCR
by: Da Mao, et al.
Published: (2025-07-01)

Role of Bifidobacterium animalis subsp. lactis BB-12 in mice with acute pancreatitis
by: Bingbing Du, et al.
Published: (2025-04-01)

Amelioration of inflammatory bowel disease by Bifidobacterium animalis subsp. lactis XLTG11 in combination with mesalazine
by: Weiwei Ma, et al.
Published: (2024-12-01)

Antibiotic Resistance in <i>Bifidobacterium animalis</i> subsp. <i>lactis</i> and <i>Bifidobacterium longum</i>: Definition of Sensitivity/Resistance Profiles at the Species Level
by: Mario Terlizzi, et al.
Published: (2025-07-01)

Bifidobacterium animalis subsp. lactis modulates early‐life immune response and gut metabolism
by: Haoming Du, et al.
Published: (2025-06-01)

Effect of Bifidobacterium animalis subsp. lactis Bi66 on Alleviating Constipation and Regulating Gut Microbiota
by: Zhixian CHEN, et al.
Published: (2025-04-01)

Synergistic defecation effects of Bifidobacterium animalis subsp. lactis BL-99 and fructooligosaccharide by modulating gut microbiota
by: Qi Zhang, et al.
Published: (2025-01-01)

Influence of probiotic strain Bifidobacterium animalis subsp. lactis lafti® b94, inulin and transglutaminase on the properties of set- style yoghurt
by: Maja Benković, et al.
Published: (2008-05-01)

The influence of lactulose on growth and survival of probiotic bacteria Lactobacillus acidophilus La-5 and Bifidobacterium animalis subsp. lactis BB-12 in reconstituted sweet whey
by: Bojan Matijević, et al.
Published: (2009-03-01)

Predictive modeling of Bifidobacterium animalis subsp. lactis Bb-12 growth in cow’s, goat’s and soy milk
by: Vedran Slačanac, et al.
Published: (2013-11-01)

Understanding the probiotic health benefits of Bifidobacterium animalis subsp. lactis, BB-12™
by: Fergus W. J. Collins, et al.
Published: (2025-07-01)

A double blinded randomized placebo trial of Bifidobacterium animalis subsp. lactis BLa80 on sleep quality and gut microbiota in healthy adults
by: Yinhua Liu, et al.
Published: (2025-04-01)

Bifidobacterium animalis subsp. lactis genome resources and metabolite profiling at the strain level and their ability to alleviate anxiety-like behavior in a sleep-deprived mouse model
by: Yao-Kun Zhang, et al.
Published: (2025-12-01)

Effect of Bifidobacterium animalis subsp. lactis Langg JZ-08 on lipid metabolism in individuals with obesity and dyslipidemia: A randomised, double-blind, and placebo-controlled trial
by: Xiaokang Niu, et al.
Published: (2025-06-01)

Proteomic Analysis of <i>Bifidobacterium animalis</i> AR668 and AR668-R1 Under Aerobic Culture
by: Yaping Liu, et al.
Published: (2025-05-01)

Bifidobacterium animalis subsp. lactis A6 alleviates perennial allergic rhinitis in adults by inhibiting serum total IgE and IL‐13: A randomized, double‐blind, placebo‐controlled trial
by: Langrun Wang, et al.
Published: (2025-06-01)

Probiotic viability, β-carotene and mineral contents, color, physicochemical and sensory properties of ice cream prepared with carrot (Daucus carota L.) puree and Bifidobacterium animalis subsp. lactis BB-12
by: Songül Çakmakçı, et al.
Published: (2025-03-01)

<i>Bifidobacterium animalis</i> Supplementation Improves Intestinal Barrier Function and Alleviates Antibiotic-Associated Diarrhea in Mice
by: Xiaoyu Du, et al.
Published: (2025-05-01)

Lactococcus lactis and Bifidobacterium bifidum alleviate postmenopausal symptoms by suppressing NF-κB signaling and microbiota dysbiosis
by: Yoon-Jung Shin, et al.
Published: (2024-12-01)

Comparative genomics of Lentilactobacillus buchneri reveals strain-level hyperdiversity and broad-spectrum CRISPR immunity against human and livestock gut phages
by: Ismail Gumustop, et al.
Published: (2025-01-01)

Comparative genomics of Lentilactobacillus buchneri reveals strain-level hyperdiversity and broad-spectrum CRISPR immunity against human and livestock gut phages.
by: Ismail Gumustop, et al.
Published: (2025-01-01)

Simultaneous Encapsulation of Probiotic Bacteria (<i>Lactococcus lactis</i>, and <i>Lactiplantibacillus plantarum</i>) in Calcium Alginate Hydrogels
by: Marko Vinceković, et al.
Published: (2025-01-01)

Preventive effects of Bifidobacterium lactis Probio-M8 on ovalbumin-induced food allergy in mice
by: Jialu Shi, et al.
Published: (2024-07-01)

Isolation, Characterization, and Assessment of Probiotic <i>Lactococcus lactis</i> from the Intestinal Tract of Largemouth Bass (<i>Micropterus salmoides</i>)
by: Xiaoyu Chen, et al.
Published: (2025-06-01)

Genomic Characterization and Safety Evaluation of <i>Enterococcus lactis</i> RB10 Isolated from Goat Feces
by: Nattarika Chaichana, et al.
Published: (2025-06-01)

Regulation of Cultivation Temperature on Biomass and Activity of <i>Bifidobacterium breve</i> B2798
by: Kailong Liu, et al.
Published: (2024-10-01)

Inhibitory effect of honey-sweetened goat and cow milk fermented with Bifidobacterium lactis Bb-12 on the growth of Listeria monocytogenes
by: Mirela Lučan, et al.
Published: (2009-06-01)

HMOs Induce Butyrate Production of <i>Faecalibacterium prausnitzii</i> via Cross-Feeding by <i>Bifidobacterium bifidum</i> with Different Mechanisms for HMO Types
by: Haruka Onodera, et al.
Published: (2025-07-01)

Oral Delivery of <i>Lactococcus lactis</i> Expressing Full-Length S Protein via Alginate–Chitosan Capsules Induces Immune Protection Against PEDV Infection in Mice
by: Miaoyan Yang, et al.
Published: (2025-04-01)

Comparative Genomics and Adaptive Evolution of <i>Bifidobacterium adolescentis</i> in Geographically Distinct Human Gut Populations
by: Pei Fu, et al.
Published: (2025-08-01)

Virulence, Antibiotic Resistance and Cytotoxic Effects of <i>Lactococcus lactis</i> Isolated from Chinese Cows with Clinical Mastitis on MAC-T Cells
by: Tiancheng Wang, et al.
Published: (2025-07-01)

Effect of Fermentation by Probiotic Bacteria on the Bioaccessibility of Bioactive Compounds from the Fruit of the Juçara Palm (<i>Euterpe edulis</i> Martius)
by: Maria Thereza Carlos Fernandes, et al.
Published: (2024-10-01)

Bifidobacterium animalis subsp. Lactis BX-BC08 modulates gut microbiota and secretes alpha-Ketoglutaric acid to alleviate MC903-induced atopic dermatitis
by: Jiamin Zhao, et al.
Published: (2025-07-01)

Cosmetically Applicable Soluble Agonists for Toll-like Receptor 2 Produced by Fermentation of Asparagus Extract Supplemented with Skimmed Milk Using <i>Lactobacillus delbrueckii</i> subsp. <i>lactis</i> TL24 Consist of Molecules Larger than 100 kDa and Can Be Stabilized by Lyophilization with Dextrin
by: Yasuhiko Komatsu, et al.
Published: (2024-09-01)

Exploring CAZymes Differences in <i>Pediococcus acidilactici</i> Strain OM681363 and <i>Lacticaseibacillus paracasei</i> Strain ON606241 Based on Whole-Genome Sequencing
by: Miao Lin, et al.
Published: (2025-02-01)

Genomic and Transcriptomic Analysis to Explore the Biological Characteristics of <i>Cyclocybe chaxingu</i>
by: Qiang Yang, et al.
Published: (2025-04-01)

Metagenomic Comparison of Gut Microbes of <i>Lemur catta</i> in Captive and Semi-Free-Range Environments
by: Chunzhong Xu, et al.
Published: (2025-05-01)

Induction of Immune Responses in Mice and Newborn Piglets by Oral Immunization with Recombinant <i>Lactococcus lactis</i> Expressing S1 and M Proteins of Porcine Epidemic Diarrhea Virus
by: Xiulei Cai, et al.
Published: (2025-03-01)

Whole-Genome Sequencing and Fine Map Analysis of <i>Pholiota nameko</i>
by: Yan He, et al.
Published: (2025-02-01)