Probing mitochondrial peroxynitrite biogenesis by a N-morpholinoarylimine-based iridium(III) complex in drug-induced liver cells
Peroxynitrite (ONOO−), a strong oxidizing agent, has an important function in the pathogenesis of various diseases, including cardiovascular, inflammatory and neurodegenerative diseases. Specifically, mitochondrial ONOO− exacerbates liver injury by driving oxidative/nitrative stress and mitochondria...
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| Main Authors: | Lingtan Kong, Ling Wang, Zixi Zhang, Liuqi Ye, Daniel Shiu-Hin Chan, Chun-Yuen Wong, Jing Wang, Chung-Hang Leung, Wanhe Wang |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-10-01
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| Series: | Redox Biology |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2213231725003180 |
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