EPILEPSY SYNDROMES WITH CONTINIUOS SPIKE AND WAVE ACTIVITY DURING SLEEP

Syndromes with continuous spikes and waves during sleep (CSWS) are being actively studied now. Etiological factors include both genetic causes and structural brain disorders; frequently – the damage of the thalamus, and congenital malformations. In most cases, the persistence of CSWS pattern leads t...

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Main Authors: O. A. Shidlovskaya, E. D. Belousova
Format: Article
Language:Russian
Published: IRBIS LLC 2017-03-01
Series:Эпилепсия и пароксизмальные состояния
Subjects:
Online Access:https://www.epilepsia.su/jour/article/view/318
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author O. A. Shidlovskaya
E. D. Belousova
author_facet O. A. Shidlovskaya
E. D. Belousova
author_sort O. A. Shidlovskaya
collection DOAJ
description Syndromes with continuous spikes and waves during sleep (CSWS) are being actively studied now. Etiological factors include both genetic causes and structural brain disorders; frequently – the damage of the thalamus, and congenital malformations. In most cases, the persistence of CSWS pattern leads to a neurocognitive dysfunction. Two mechanisms of the intellectual regression are supposed: a violation of brain maturation processes and the effect of the remote inhibition. The most effective treatment is considered to be a combination of hormones and antiepileptic drugs. It is often possible to restore a normal level of child development in case of the early diagnosis and rational therapeutic tactics. However, if more than 18 months has passed since the onset of seizures, as a rule, intellectual functions can’t be improved.
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series Эпилепсия и пароксизмальные состояния
spelling doaj-art-4fc3d44b422f4b8ea3c3e0dfa4428ea52025-08-20T03:19:34ZrusIRBIS LLCЭпилепсия и пароксизмальные состояния2077-83332311-40882017-03-0184586610.17749/2077-8333.2016.8.4.058-066313EPILEPSY SYNDROMES WITH CONTINIUOS SPIKE AND WAVE ACTIVITY DURING SLEEPO. A. Shidlovskaya0E. D. Belousova1FSBE HEN. I. Pirogov RNRMU MOH RussiaFSBE HEN. I. Pirogov RNRMU MOH RussiaSyndromes with continuous spikes and waves during sleep (CSWS) are being actively studied now. Etiological factors include both genetic causes and structural brain disorders; frequently – the damage of the thalamus, and congenital malformations. In most cases, the persistence of CSWS pattern leads to a neurocognitive dysfunction. Two mechanisms of the intellectual regression are supposed: a violation of brain maturation processes and the effect of the remote inhibition. The most effective treatment is considered to be a combination of hormones and antiepileptic drugs. It is often possible to restore a normal level of child development in case of the early diagnosis and rational therapeutic tactics. However, if more than 18 months has passed since the onset of seizures, as a rule, intellectual functions can’t be improved.https://www.epilepsia.su/jour/article/view/318epilepsychildrencontinious spike-wave activity during sleepeses/cswsеpileptic encephalopathytreatment
spellingShingle O. A. Shidlovskaya
E. D. Belousova
EPILEPSY SYNDROMES WITH CONTINIUOS SPIKE AND WAVE ACTIVITY DURING SLEEP
Эпилепсия и пароксизмальные состояния
epilepsy
children
continious spike-wave activity during sleep
eses/csws
еpileptic encephalopathy
treatment
title EPILEPSY SYNDROMES WITH CONTINIUOS SPIKE AND WAVE ACTIVITY DURING SLEEP
title_full EPILEPSY SYNDROMES WITH CONTINIUOS SPIKE AND WAVE ACTIVITY DURING SLEEP
title_fullStr EPILEPSY SYNDROMES WITH CONTINIUOS SPIKE AND WAVE ACTIVITY DURING SLEEP
title_full_unstemmed EPILEPSY SYNDROMES WITH CONTINIUOS SPIKE AND WAVE ACTIVITY DURING SLEEP
title_short EPILEPSY SYNDROMES WITH CONTINIUOS SPIKE AND WAVE ACTIVITY DURING SLEEP
title_sort epilepsy syndromes with continiuos spike and wave activity during sleep
topic epilepsy
children
continious spike-wave activity during sleep
eses/csws
еpileptic encephalopathy
treatment
url https://www.epilepsia.su/jour/article/view/318
work_keys_str_mv AT oashidlovskaya epilepsysyndromeswithcontiniuosspikeandwaveactivityduringsleep
AT edbelousova epilepsysyndromeswithcontiniuosspikeandwaveactivityduringsleep