Haemangioendothelioma of Different Sites: A Series of Four Cases
Haemangioendothelioma is a rare vascular tumour of endothelial origin. It is considered a tumour with intermediate malignant potential. It is locally aggressive and can occasionally metastasize. Four cases of epithelioid haemangioendothelioma have been reported in a tertiary medical centre in the De...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
JCDR Research and Publications Private Limited
2025-05-01
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| Series: | Journal of Clinical and Diagnostic Research |
| Subjects: | |
| Online Access: | https://jcdr.net/articles/PDF/20982/76234_CE[Ra1]_F(IS)_QC(PS_SS)_PF1(RI_SL)_redo_PFA(IS)_PB(RI_IS)_PN(IS).pdf |
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| Summary: | Haemangioendothelioma is a rare vascular tumour of endothelial origin. It is considered a tumour with intermediate malignant potential. It is locally aggressive and can occasionally metastasize. Four cases of epithelioid haemangioendothelioma have been reported in a tertiary medical centre in the Department of Pathology, Government Medical College, Kottayam, Kerala, India, over a span of two years, specifically between August 2022 and August 2024. Two of the cases involved 10-year-old girls who presented with hoarseness of voice for six months and swelling in the thigh for three years, respectively. The third case was that of a 43-year-old female with a lesion in the liver. The fourth case involved a 48-year-old male who presented with swelling in the left arm. Microscopy of all cases revealed a neoplasm with numerous small-sized blood vessels lined by plump endothelial cells. Immunohistochemistry (IHC) was performed, leading to a diagnosis of haemangioendothelioma. The estimated prevalence of this tumour is less than one in a million, which makes the present study the first of its kind. |
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| ISSN: | 2249-782X 0973-709X |