Pharmacovigilance in the digital age: gaining insight from social media data

Pharmacovigilance is essential for protecting patient health by monitoring and managing medication-related risks. Traditional methods like spontaneous reporting systems and clinical trials are valuable for identifying adverse drug events, but face delays in data access. Social media platforms, with...

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Main Authors: Fan Dong, Wenjing Guo, Jie Liu, Tucker A. Patterson, Huixiao Hong
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Experimental Biology and Medicine
Subjects:
Online Access:https://www.ebm-journal.org/articles/10.3389/ebm.2025.10555/full
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author Fan Dong
Wenjing Guo
Jie Liu
Tucker A. Patterson
Huixiao Hong
author_facet Fan Dong
Wenjing Guo
Jie Liu
Tucker A. Patterson
Huixiao Hong
author_sort Fan Dong
collection DOAJ
description Pharmacovigilance is essential for protecting patient health by monitoring and managing medication-related risks. Traditional methods like spontaneous reporting systems and clinical trials are valuable for identifying adverse drug events, but face delays in data access. Social media platforms, with their real-time data, offer a novel avenue for pharmacovigilance by providing a wealth of user-generated content on medication usage, adverse drug events, and public sentiment. However, the unstructured nature of social media content presents challenges in data analysis, including variability and potential biases. Advanced techniques like natural language processing and machine learning are increasingly being employed to extract meaningful information from social media data, aiding in early adverse drug event detection and real-time medication safety monitoring. Ensuring data reliability and addressing ethical considerations are crucial in this context. This review examines the existing literature on the use of social media data for drug safety analysis, highlighting the platforms involved, methodologies applied, and research questions explored. It also discusses the challenges, limitations, and future directions of this emerging field, emphasizing the need for ethical principles, transparency, and interdisciplinary collaboration to maximize the potential of social media in enhancing pharmacovigilance efforts.
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spelling doaj-art-4fb302c4988e45d3bc4f1705e38ab6b52025-08-20T03:12:24ZengFrontiers Media S.A.Experimental Biology and Medicine1535-36992025-05-0125010.3389/ebm.2025.1055510555Pharmacovigilance in the digital age: gaining insight from social media dataFan DongWenjing GuoJie LiuTucker A. PattersonHuixiao HongPharmacovigilance is essential for protecting patient health by monitoring and managing medication-related risks. Traditional methods like spontaneous reporting systems and clinical trials are valuable for identifying adverse drug events, but face delays in data access. Social media platforms, with their real-time data, offer a novel avenue for pharmacovigilance by providing a wealth of user-generated content on medication usage, adverse drug events, and public sentiment. However, the unstructured nature of social media content presents challenges in data analysis, including variability and potential biases. Advanced techniques like natural language processing and machine learning are increasingly being employed to extract meaningful information from social media data, aiding in early adverse drug event detection and real-time medication safety monitoring. Ensuring data reliability and addressing ethical considerations are crucial in this context. This review examines the existing literature on the use of social media data for drug safety analysis, highlighting the platforms involved, methodologies applied, and research questions explored. It also discusses the challenges, limitations, and future directions of this emerging field, emphasizing the need for ethical principles, transparency, and interdisciplinary collaboration to maximize the potential of social media in enhancing pharmacovigilance efforts.https://www.ebm-journal.org/articles/10.3389/ebm.2025.10555/fulldrug safetyartificial intelligencemachine learningnatural language processingsocial mediapost-market surveillance
spellingShingle Fan Dong
Wenjing Guo
Jie Liu
Tucker A. Patterson
Huixiao Hong
Pharmacovigilance in the digital age: gaining insight from social media data
Experimental Biology and Medicine
drug safety
artificial intelligence
machine learning
natural language processing
social media
post-market surveillance
title Pharmacovigilance in the digital age: gaining insight from social media data
title_full Pharmacovigilance in the digital age: gaining insight from social media data
title_fullStr Pharmacovigilance in the digital age: gaining insight from social media data
title_full_unstemmed Pharmacovigilance in the digital age: gaining insight from social media data
title_short Pharmacovigilance in the digital age: gaining insight from social media data
title_sort pharmacovigilance in the digital age gaining insight from social media data
topic drug safety
artificial intelligence
machine learning
natural language processing
social media
post-market surveillance
url https://www.ebm-journal.org/articles/10.3389/ebm.2025.10555/full
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