Prospectively assessed hypothalamic-pituitary dysfunction after proton therapy in adults with head and neck, skull base and brain tumors

Prospectively assessed hypothalamic-pituitary dysfunction after proton therapy in adults with head and neck, skull base and brain tumors

Abstract Radiotherapy is advocated for many brain and head and neck tumors close to the pituitary gland. Pituitary hormones govern many vital functions but data of standardized monitoring for deficiencies after irradiation are lacking. We prospectively assessed the latency and frequency of hypothala...

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Bibliographic Details
Main Authors: Jordan Bouter, Nathan Azemar, Anthony Vela, Pauline Dutheil, Paul Lesueur, Dinu Stefan, Yves Reznik, Juliette Thariat
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Scientific Reports
Subjects:
Tumor
Brain
Head and neck
Hypopituitarism
Endocrine
Radiotherapy
Online Access:https://doi.org/10.1038/s41598-025-16960-z
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