Secondary Myelitis in Dermal Sinus Causing Paraplegia in a Child with Previously Normal Neurological Function

Neural tube defects result from failure of neural tube fusion during early embryogenesis, the fourth week after conception. The spectrum of severity is not uniform across the various forms of this congenital anomaly as certain presentations are not compatible with extrauterine life (anencephaly) whi...

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Main Authors: Sakina Rashid, Grace Kinabo, Marissa Kellogg, William P. Howlett, Marieke C. J. Dekker
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Case Reports in Neurological Medicine
Online Access:http://dx.doi.org/10.1155/2016/8918954
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author Sakina Rashid
Grace Kinabo
Marissa Kellogg
William P. Howlett
Marieke C. J. Dekker
author_facet Sakina Rashid
Grace Kinabo
Marissa Kellogg
William P. Howlett
Marieke C. J. Dekker
author_sort Sakina Rashid
collection DOAJ
description Neural tube defects result from failure of neural tube fusion during early embryogenesis, the fourth week after conception. The spectrum of severity is not uniform across the various forms of this congenital anomaly as certain presentations are not compatible with extrauterine life (anencephaly) while, on the other hand, other defects may remain undiagnosed as they are entirely asymptomatic (occult spina bifida). We report a child with previously normal neurological development, a devastating clinical course following superinfection of a subtle spina bifida defect which resulted in a flaccid paralysis below the level of the lesion and permanent neurological deficits following resolution of the acute infection and a back closure surgery.
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2090-6676
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series Case Reports in Neurological Medicine
spelling doaj-art-4f7662374f814184ab828e3d93724d2d2025-08-20T02:05:36ZengWileyCase Reports in Neurological Medicine2090-66682090-66762016-01-01201610.1155/2016/89189548918954Secondary Myelitis in Dermal Sinus Causing Paraplegia in a Child with Previously Normal Neurological FunctionSakina Rashid0Grace Kinabo1Marissa Kellogg2William P. Howlett3Marieke C. J. Dekker4Department of Pediatrics, Kilimanjaro Christian Medical Centre, Moshi, TanzaniaDepartment of Pediatrics, Kilimanjaro Christian Medical Centre, Moshi, TanzaniaStanford University, Palo Alto, CA, USADepartment of Internal Medicine, Kilimanjaro Christian Medical Centre, Moshi, TanzaniaDepartment of Pediatrics, Kilimanjaro Christian Medical Centre, Moshi, TanzaniaNeural tube defects result from failure of neural tube fusion during early embryogenesis, the fourth week after conception. The spectrum of severity is not uniform across the various forms of this congenital anomaly as certain presentations are not compatible with extrauterine life (anencephaly) while, on the other hand, other defects may remain undiagnosed as they are entirely asymptomatic (occult spina bifida). We report a child with previously normal neurological development, a devastating clinical course following superinfection of a subtle spina bifida defect which resulted in a flaccid paralysis below the level of the lesion and permanent neurological deficits following resolution of the acute infection and a back closure surgery.http://dx.doi.org/10.1155/2016/8918954
spellingShingle Sakina Rashid
Grace Kinabo
Marissa Kellogg
William P. Howlett
Marieke C. J. Dekker
Secondary Myelitis in Dermal Sinus Causing Paraplegia in a Child with Previously Normal Neurological Function
Case Reports in Neurological Medicine
title Secondary Myelitis in Dermal Sinus Causing Paraplegia in a Child with Previously Normal Neurological Function
title_full Secondary Myelitis in Dermal Sinus Causing Paraplegia in a Child with Previously Normal Neurological Function
title_fullStr Secondary Myelitis in Dermal Sinus Causing Paraplegia in a Child with Previously Normal Neurological Function
title_full_unstemmed Secondary Myelitis in Dermal Sinus Causing Paraplegia in a Child with Previously Normal Neurological Function
title_short Secondary Myelitis in Dermal Sinus Causing Paraplegia in a Child with Previously Normal Neurological Function
title_sort secondary myelitis in dermal sinus causing paraplegia in a child with previously normal neurological function
url http://dx.doi.org/10.1155/2016/8918954
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