Thrombotic Microangiopathy with Skin Localization Secondary to Cytarabine-Daunorubicin Association: Report of a Case
The thrombotic microangiopathy is a syndrome characterized by the combination of mechanical hemolytic anemia, peripheral thrombocytopenia, and organ failure of variable severity. In addition to the idiopathic form, several cases are identified as secondary to pregnancy, infections, disease systems,...
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| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | Case Reports in Hematology |
| Online Access: | http://dx.doi.org/10.1155/2012/806476 |
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| author | S. Regragui S. Amelal S. Astati M. Zine N. Alami Drideb A. Al Bouzidi N. Messaoudi M. Benkirane K. Doghmi M. Mikdame |
| author_facet | S. Regragui S. Amelal S. Astati M. Zine N. Alami Drideb A. Al Bouzidi N. Messaoudi M. Benkirane K. Doghmi M. Mikdame |
| author_sort | S. Regragui |
| collection | DOAJ |
| description | The thrombotic microangiopathy is a syndrome characterized by the combination of mechanical hemolytic anemia, peripheral thrombocytopenia, and organ failure of variable severity. In addition to the idiopathic form, several cases are identified as secondary to pregnancy, infections, disease systems, organ transplants, and cancer. Other forms are secondary to drugs including antimitotics. We report the case of a patient followed for acute myelogenous leukemia. She received induction chemotherapy combining daunorubicin and cytarabine, complicated by thrombotic thrombocytopenic purpura. |
| format | Article |
| id | doaj-art-4f737f10a3ef412f8d7c18b8db9304b2 |
| institution | OA Journals |
| issn | 2090-6560 2090-6579 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Hematology |
| spelling | doaj-art-4f737f10a3ef412f8d7c18b8db9304b22025-08-20T02:05:36ZengWileyCase Reports in Hematology2090-65602090-65792012-01-01201210.1155/2012/806476806476Thrombotic Microangiopathy with Skin Localization Secondary to Cytarabine-Daunorubicin Association: Report of a CaseS. Regragui0S. Amelal1S. Astati2M. Zine3N. Alami Drideb4A. Al Bouzidi5N. Messaoudi6M. Benkirane7K. Doghmi8M. Mikdame9Department of Clinical Hematology, Military Hospital Mohammed V, Rabat, MoroccoDepartment of Clinical Hematology, Military Hospital Mohammed V, Rabat, MoroccoDepartment of Clinical Hematology, Military Hospital Mohammed V, Rabat, MoroccoDepartment of Clinical Hematology, Military Hospital Mohammed V, Rabat, MoroccoDepartment of Clinical Hematology, Military Hospital Mohammed V, Rabat, MoroccoDepartment of Pathology, Military Hospital Mohammed V, Rabat, MoroccoDepartment of Biological Hematology, Military Hospital Mohammed V, Rabat, MoroccoBlood Transfusion Centre, Military Hospital Mohammed V, Rabat, MoroccoDepartment of Clinical Hematology, Military Hospital Mohammed V, Rabat, MoroccoDepartment of Clinical Hematology, Military Hospital Mohammed V, Rabat, MoroccoThe thrombotic microangiopathy is a syndrome characterized by the combination of mechanical hemolytic anemia, peripheral thrombocytopenia, and organ failure of variable severity. In addition to the idiopathic form, several cases are identified as secondary to pregnancy, infections, disease systems, organ transplants, and cancer. Other forms are secondary to drugs including antimitotics. We report the case of a patient followed for acute myelogenous leukemia. She received induction chemotherapy combining daunorubicin and cytarabine, complicated by thrombotic thrombocytopenic purpura.http://dx.doi.org/10.1155/2012/806476 |
| spellingShingle | S. Regragui S. Amelal S. Astati M. Zine N. Alami Drideb A. Al Bouzidi N. Messaoudi M. Benkirane K. Doghmi M. Mikdame Thrombotic Microangiopathy with Skin Localization Secondary to Cytarabine-Daunorubicin Association: Report of a Case Case Reports in Hematology |
| title | Thrombotic Microangiopathy with Skin Localization Secondary to Cytarabine-Daunorubicin Association: Report of a Case |
| title_full | Thrombotic Microangiopathy with Skin Localization Secondary to Cytarabine-Daunorubicin Association: Report of a Case |
| title_fullStr | Thrombotic Microangiopathy with Skin Localization Secondary to Cytarabine-Daunorubicin Association: Report of a Case |
| title_full_unstemmed | Thrombotic Microangiopathy with Skin Localization Secondary to Cytarabine-Daunorubicin Association: Report of a Case |
| title_short | Thrombotic Microangiopathy with Skin Localization Secondary to Cytarabine-Daunorubicin Association: Report of a Case |
| title_sort | thrombotic microangiopathy with skin localization secondary to cytarabine daunorubicin association report of a case |
| url | http://dx.doi.org/10.1155/2012/806476 |
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