Relationship between regional volume changes and water diffusion in fixed marmoset brains: an in vivo and ex vivo comparison

Abstract Ex vivo studies of the brain are often employed as experimental systems in neuroscience. In general, brains for ex vivo MRI studies are usually fixed with paraformaldehyde to preserve molecular structure and prevent tissue destruction during long-term storage. As a result, fixing brain tiss...

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Main Authors: Daisuke Yoshimaru, Tomokazu Tsurugizawa, Naoya Hayashi, Junichi Hata, Shuhei Shibukawa, Kei Hagiya, Hinako Oshiro, Noriyuki Kishi, Kazuhiro Saito, Hideyuki Okano, Hirotaka James Okano
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-78246-0
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