Acanthosis Nigricans Associated with an Adrenocortical Tumor in a Pediatric Patient

Malignant acanthosis nigricans (AN) is a rare paraneoplastic syndrome seen primarily in adults with an underlying diagnosis of gastrointestinal adenocarcinoma. Malignant AN is characterized by hyperpigmentation and velvety hyperplasia of the epidermis. This condition is generally not associated with...

Full description

Saved in:
Bibliographic Details
Main Authors: Elizabeth Isaacoff, Filippina Filia Dimitriadi, Frank Barrows, Bruce Pawel, Peter Mattei, Sogol Mostoufi-Moab
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Case Reports in Endocrinology
Online Access:http://dx.doi.org/10.1155/2013/174593
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1850224484160634880
author Elizabeth Isaacoff
Filippina Filia Dimitriadi
Frank Barrows
Bruce Pawel
Peter Mattei
Sogol Mostoufi-Moab
author_facet Elizabeth Isaacoff
Filippina Filia Dimitriadi
Frank Barrows
Bruce Pawel
Peter Mattei
Sogol Mostoufi-Moab
author_sort Elizabeth Isaacoff
collection DOAJ
description Malignant acanthosis nigricans (AN) is a rare paraneoplastic syndrome seen primarily in adults with an underlying diagnosis of gastrointestinal adenocarcinoma. Malignant AN is characterized by hyperpigmentation and velvety hyperplasia of the epidermis. This condition is generally not associated with tumors in pediatric populations or in the adrenal gland. We present a case of malignant AN in a pediatric patient with a nonmalignant, functional adrenocortical tumor.
format Article
id doaj-art-4f6b97d60d3f4f6c904a57046e6fd089
institution OA Journals
issn 2090-6501
2090-651X
language English
publishDate 2013-01-01
publisher Wiley
record_format Article
series Case Reports in Endocrinology
spelling doaj-art-4f6b97d60d3f4f6c904a57046e6fd0892025-08-20T02:05:36ZengWileyCase Reports in Endocrinology2090-65012090-651X2013-01-01201310.1155/2013/174593174593Acanthosis Nigricans Associated with an Adrenocortical Tumor in a Pediatric PatientElizabeth Isaacoff0Filippina Filia Dimitriadi1Frank Barrows2Bruce Pawel3Peter Mattei4Sogol Mostoufi-Moab5Department of Pediatrics, The Children's Hospital of Philadelphia, 34th Street and Civic Center Boulevard, 3535 Market Street, Room 1562, Philadelphia, PA 19104, USADivision of Pediatric Endocrinology, St. Christopher's Hospital for Children, 3601 A. Street, Philadelphia, PA 19134, USADivision of Pediatric Endocrinology, Monmouth Medical Children's Hospital, 180 Avenue at the Commons, Suite 7B, Shrewsbury, NJ 07702, USADepartment of Pathology, The Children's Hospital of Philadelphia, 34th Street and Civic Center Boulevard, Philadelphia, PA 19104, USADepartment of General Surgery, The Children's Hospital of Philadelphia, 34th Street and Civic Center Boulevard, Philadelphia, PA 19104, USADepartment of Pediatrics, The Children's Hospital of Philadelphia, 34th Street and Civic Center Boulevard, 3535 Market Street, Room 1562, Philadelphia, PA 19104, USAMalignant acanthosis nigricans (AN) is a rare paraneoplastic syndrome seen primarily in adults with an underlying diagnosis of gastrointestinal adenocarcinoma. Malignant AN is characterized by hyperpigmentation and velvety hyperplasia of the epidermis. This condition is generally not associated with tumors in pediatric populations or in the adrenal gland. We present a case of malignant AN in a pediatric patient with a nonmalignant, functional adrenocortical tumor.http://dx.doi.org/10.1155/2013/174593
spellingShingle Elizabeth Isaacoff
Filippina Filia Dimitriadi
Frank Barrows
Bruce Pawel
Peter Mattei
Sogol Mostoufi-Moab
Acanthosis Nigricans Associated with an Adrenocortical Tumor in a Pediatric Patient
Case Reports in Endocrinology
title Acanthosis Nigricans Associated with an Adrenocortical Tumor in a Pediatric Patient
title_full Acanthosis Nigricans Associated with an Adrenocortical Tumor in a Pediatric Patient
title_fullStr Acanthosis Nigricans Associated with an Adrenocortical Tumor in a Pediatric Patient
title_full_unstemmed Acanthosis Nigricans Associated with an Adrenocortical Tumor in a Pediatric Patient
title_short Acanthosis Nigricans Associated with an Adrenocortical Tumor in a Pediatric Patient
title_sort acanthosis nigricans associated with an adrenocortical tumor in a pediatric patient
url http://dx.doi.org/10.1155/2013/174593
work_keys_str_mv AT elizabethisaacoff acanthosisnigricansassociatedwithanadrenocorticaltumorinapediatricpatient
AT filippinafiliadimitriadi acanthosisnigricansassociatedwithanadrenocorticaltumorinapediatricpatient
AT frankbarrows acanthosisnigricansassociatedwithanadrenocorticaltumorinapediatricpatient
AT brucepawel acanthosisnigricansassociatedwithanadrenocorticaltumorinapediatricpatient
AT petermattei acanthosisnigricansassociatedwithanadrenocorticaltumorinapediatricpatient
AT sogolmostoufimoab acanthosisnigricansassociatedwithanadrenocorticaltumorinapediatricpatient