Health-related quality of life of patients on antiretroviral therapy at the Federal Medical Center, Makurdi, Nigeria

Context: Health related quality of life (HRQL) indices could provide information about the effects of disease progression and the effectiveness of medical interventions that cannot be obtained using objective clinical measures. Aim: The aim of this study is to assess HRQL of patients on highly activ...

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Main Authors: Vivian Shaahu, Wasiu Adebimpe, Michael Asuzu, D Belabo, O Popoola, O Uchendu
Format: Article
Language:English
Published: Thieme Medical and Scientific Publishers Pvt. Ltd. 2019-07-01
Series:Libyan International Medical University Journal
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Online Access:http://www.thieme-connect.de/DOI/DOI?10.4103/LIUJ.LIUJ_26_19
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author Vivian Shaahu
Wasiu Adebimpe
Michael Asuzu
D Belabo
O Popoola
O Uchendu
author_facet Vivian Shaahu
Wasiu Adebimpe
Michael Asuzu
D Belabo
O Popoola
O Uchendu
author_sort Vivian Shaahu
collection DOAJ
description Context: Health related quality of life (HRQL) indices could provide information about the effects of disease progression and the effectiveness of medical interventions that cannot be obtained using objective clinical measures. Aim: The aim of this study is to assess HRQL of patients on highly active antiretroviral therapy (HAART) at the Federal Medical Center, Makurdi in North Central Nigeria. Settings and Design: The study was a cross-sectional survey among people living with HIV/AIDs (PLWHAs) on HAART. Methods: The 546 PLWHAs on HAART were selected using systematic sampling technique. A modification of the 36-Item Short-Form Health Survey Version 2 questionnaire was used to assess respondents' HRQL in eight dimensions: Physical functioning (PF), role-physical (RP), role-emotional (RE), social functioning (SF), bodily pain (BP), vitality (VT), mental health (MH), and general health (GH). Data generated after measuring and scoring HRQL using standard methods were analyzed using the SPSS 17. Results: Good HRQL ratings included: PF (98.9%), RE (98.7%), SF (98.2%), VT (96.9%), RP (96.5%), MH (96.3%), BP (94.1%), and GH (93.4%). Predictors of good HRQL were as follows: Age <40 years (odds ratio [OR] = 4.26, confidence interval [CI] = 1.49–12.11) and being currently employed (OR = 3.20, CI = 1.08–9.49) (RP); and having a caregiver (OR = 4.94, CI = 1.33–18.27). Predictors of less likelihood of good HRQL were: Enjoying social support (OR = 0.12, CI = 0.03–0.55) (RP; MH); being without spouse/partner (OR = 0.43, CI = 0.21–0.91) (GH). Conclusions: HAART improves HRQL of HIV patients. Clinicians need to be responsive to factors related to disclosure, having a caregiver, and social support as a means of improving HRQL.
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spelling doaj-art-4f6699bfbf6e40c6853cd190a42fcd8b2025-08-20T03:18:09ZengThieme Medical and Scientific Publishers Pvt. Ltd.Libyan International Medical University Journal2519-139X2019-07-010402828810.4103/LIUJ.LIUJ_26_19Health-related quality of life of patients on antiretroviral therapy at the Federal Medical Center, Makurdi, NigeriaVivian Shaahu0Wasiu Adebimpe1Michael Asuzu2D Belabo3O Popoola4O Uchendu5Department of Community Medicine, Federal Medical Centre, Makurdi, NigeriaDepartment of Community Medicine, University of Medical Sciences, Ondo, NigeriaDepartment of Community Medicine, University of Medical Sciences, Ondo, NigeriaDepartment of Community Medicine, University College Hospital/University of Ibadan, Ibadan, NigeriaDepartment of Community Medicine, University College Hospital/University of Ibadan, Ibadan, NigeriaDepartment of Community Medicine, University College Hospital/University of Ibadan, Ibadan, NigeriaContext: Health related quality of life (HRQL) indices could provide information about the effects of disease progression and the effectiveness of medical interventions that cannot be obtained using objective clinical measures. Aim: The aim of this study is to assess HRQL of patients on highly active antiretroviral therapy (HAART) at the Federal Medical Center, Makurdi in North Central Nigeria. Settings and Design: The study was a cross-sectional survey among people living with HIV/AIDs (PLWHAs) on HAART. Methods: The 546 PLWHAs on HAART were selected using systematic sampling technique. A modification of the 36-Item Short-Form Health Survey Version 2 questionnaire was used to assess respondents' HRQL in eight dimensions: Physical functioning (PF), role-physical (RP), role-emotional (RE), social functioning (SF), bodily pain (BP), vitality (VT), mental health (MH), and general health (GH). Data generated after measuring and scoring HRQL using standard methods were analyzed using the SPSS 17. Results: Good HRQL ratings included: PF (98.9%), RE (98.7%), SF (98.2%), VT (96.9%), RP (96.5%), MH (96.3%), BP (94.1%), and GH (93.4%). Predictors of good HRQL were as follows: Age <40 years (odds ratio [OR] = 4.26, confidence interval [CI] = 1.49–12.11) and being currently employed (OR = 3.20, CI = 1.08–9.49) (RP); and having a caregiver (OR = 4.94, CI = 1.33–18.27). Predictors of less likelihood of good HRQL were: Enjoying social support (OR = 0.12, CI = 0.03–0.55) (RP; MH); being without spouse/partner (OR = 0.43, CI = 0.21–0.91) (GH). Conclusions: HAART improves HRQL of HIV patients. Clinicians need to be responsive to factors related to disclosure, having a caregiver, and social support as a means of improving HRQL.http://www.thieme-connect.de/DOI/DOI?10.4103/LIUJ.LIUJ_26_19health-related quality of lifehighly active antiretroviral therapyhivmakurdi
spellingShingle Vivian Shaahu
Wasiu Adebimpe
Michael Asuzu
D Belabo
O Popoola
O Uchendu
Health-related quality of life of patients on antiretroviral therapy at the Federal Medical Center, Makurdi, Nigeria
Libyan International Medical University Journal
health-related quality of life
highly active antiretroviral therapy
hiv
makurdi
title Health-related quality of life of patients on antiretroviral therapy at the Federal Medical Center, Makurdi, Nigeria
title_full Health-related quality of life of patients on antiretroviral therapy at the Federal Medical Center, Makurdi, Nigeria
title_fullStr Health-related quality of life of patients on antiretroviral therapy at the Federal Medical Center, Makurdi, Nigeria
title_full_unstemmed Health-related quality of life of patients on antiretroviral therapy at the Federal Medical Center, Makurdi, Nigeria
title_short Health-related quality of life of patients on antiretroviral therapy at the Federal Medical Center, Makurdi, Nigeria
title_sort health related quality of life of patients on antiretroviral therapy at the federal medical center makurdi nigeria
topic health-related quality of life
highly active antiretroviral therapy
hiv
makurdi
url http://www.thieme-connect.de/DOI/DOI?10.4103/LIUJ.LIUJ_26_19
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AT michaelasuzu healthrelatedqualityoflifeofpatientsonantiretroviraltherapyatthefederalmedicalcentermakurdinigeria
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AT opopoola healthrelatedqualityoflifeofpatientsonantiretroviraltherapyatthefederalmedicalcentermakurdinigeria
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