Consensus guidelines for the management of primary central nervous system lymphoma for low and middle-income countries
Primary lymphoma of the central nervous system (PCNSL) is a rare and aggressive form of extranodal non-Hodgkin lymphoma primarily involving the brain, spinal cord, cerebrospinal fluid, and eyes. The role of surgical intervention in PCNSL is currently limited to biopsy and decompression of critical...
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| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Pakistan Medical Association
2024-06-01
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| Series: | Journal of the Pakistan Medical Association |
| Online Access: | https://jpma.org.pk/index.php/public_html/article/view/21196 |
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| Summary: | Primary lymphoma of the central nervous system (PCNSL)
is a rare and aggressive form of extranodal non-Hodgkin
lymphoma primarily involving the brain, spinal cord,
cerebrospinal fluid, and eyes. The role of surgical
intervention in PCNSL is currently limited to biopsy and
decompression of critical structures if needed – extended
resection is debated. Chemotherapy is the mainstay of
treatment. In lower and middle-income countries (LMICs),
issues like delayed diagnosis and resource constraints are
widespread. These guidelines provide a framework for
addressing PCNSL in LMICs, emphasizing the importance
of early diagnosis, tailored treatment approaches, and
ongoing patient monitoring to improve outcomes for this
rare and aggressive disease.
Keywords: Lymphoma, non-Hodgkin, biopsy, nervous
system, physiologic decompression, spinal cord, brain
tumours
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| ISSN: | 0030-9982 |