Cancer therapeutic implications of microRNAs in the regulation of immune checkpoint blockade
Abstract Dampening of patients’ immune response to tumor-specific antigens is a major reason for tumor development and progression. Within tumor microenvironment, aberrant expression of immune checkpoints changes T lymphocyte activity, and induces immune tolerance or escape. Inhibiting these checkpo...
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| Main Authors: | Yan Zhang, Toshihiko Tanno, Chrysi Kanellopoulou |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
ELS Publishing (ELSP)
2019-08-01
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| Series: | ExRNA |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s41544-019-0022-0 |
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