3D cell aggregates amplify diffusion signals.

Biophysical models can predict the behavior of cell cultures including 3D cell aggregates (3DCAs), thereby reducing the need for costly and time-consuming experiments. Specifically, mass transfer models enable studying the transport of nutrients, oxygen, signaling molecules, and drugs in 3DCA. These...

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Bibliographic Details
Main Authors: Hamidreza Arjmandi, Kajsa P Kanebratt, Liisa Vilén, Peter Gennemark, Adam Noel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0310109
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