Knowledge, attitude, and practice toward vitiligo among vitiligo patients: a mediation analysis
Abstract Knowing provoking factors of vitiligo progression and how to avoid them is essential to the successful self-management of vitiligo. Cultivating a positive attitude is also essential to avoid focusing on the negative aspects of the disease and to fuel proactive practice. This study aims to e...
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Nature Portfolio
2025-02-01
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| author | Hua Feng Xiulian Xu Shuzhen Qi Kun Chen Mei Ju Xiaofang Li Shuxian Shang |
| author_facet | Hua Feng Xiulian Xu Shuzhen Qi Kun Chen Mei Ju Xiaofang Li Shuxian Shang |
| author_sort | Hua Feng |
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| description | Abstract Knowing provoking factors of vitiligo progression and how to avoid them is essential to the successful self-management of vitiligo. Cultivating a positive attitude is also essential to avoid focusing on the negative aspects of the disease and to fuel proactive practice. This study aims to evaluate the knowledge, attitudes, and practices (KAP) of vitiligo patients and identify related factors. The study recruited 517 (54.55% male) adult vitiligo patients in Beijing and Nanjing. The mean knowledge, attitude, and practice scores were 5.45 ± 2.74 (possible range: 0–10), 23.15 ± 6.78 (possible range: 8–40), and 37.13 ± 6.78 (possible range: 10–50), respectively. Mediation analysis indicated that knowledge (β = 0.24, P = 0.023), attitude (β=-0.28, P < 0.001), disease duration (β=-1.49, P < 0.001), and negative emotions (β=-1.54, P = 0.008) had direct effects on practice. Income (β=-0.29, P = 0.003), disease duration (β = 0.16, P = 0.033), lesion duration (β = 0.25, P = 0.003), education (β = 0.11, P = 0.024), and age (β=-0.14, P = 0.036) had indirect effects on practice. Vitiligo patients exhibited significant gaps in knowledge and attitudes toward their condition despite active management practices. Given the chronic nature of vitiligo and its slow treatment response, tailored health education strategies focusing on improving knowledge and attitudes are essential for standardizing treatment and enhancing patient adherence. |
| format | Article |
| id | doaj-art-4f4ecb8154434558af274f2ad14a75a8 |
| institution | Kabale University |
| issn | 2045-2322 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Nature Portfolio |
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| series | Scientific Reports |
| spelling | doaj-art-4f4ecb8154434558af274f2ad14a75a82025-02-09T12:32:05ZengNature PortfolioScientific Reports2045-23222025-02-011511910.1038/s41598-025-89346-wKnowledge, attitude, and practice toward vitiligo among vitiligo patients: a mediation analysisHua Feng0Xiulian Xu1Shuzhen Qi2Kun Chen3Mei Ju4Xiaofang Li5Shuxian Shang6Department of Dermatology, Beijing Tiantan Hospital, Capital Medical UniversityHospital of Dermatology, Chinese Academy of Medical Sciences & Peking Union Medical CollegeHospital of Dermatology, Chinese Academy of Medical Sciences & Peking Union Medical CollegeHospital of Dermatology, Chinese Academy of Medical Sciences & Peking Union Medical CollegeHospital of Dermatology, Chinese Academy of Medical Sciences & Peking Union Medical CollegeHospital of Dermatology, Chinese Academy of Medical Sciences & Peking Union Medical CollegeHospital of Dermatology, Chinese Academy of Medical Sciences & Peking Union Medical CollegeAbstract Knowing provoking factors of vitiligo progression and how to avoid them is essential to the successful self-management of vitiligo. Cultivating a positive attitude is also essential to avoid focusing on the negative aspects of the disease and to fuel proactive practice. This study aims to evaluate the knowledge, attitudes, and practices (KAP) of vitiligo patients and identify related factors. The study recruited 517 (54.55% male) adult vitiligo patients in Beijing and Nanjing. The mean knowledge, attitude, and practice scores were 5.45 ± 2.74 (possible range: 0–10), 23.15 ± 6.78 (possible range: 8–40), and 37.13 ± 6.78 (possible range: 10–50), respectively. Mediation analysis indicated that knowledge (β = 0.24, P = 0.023), attitude (β=-0.28, P < 0.001), disease duration (β=-1.49, P < 0.001), and negative emotions (β=-1.54, P = 0.008) had direct effects on practice. Income (β=-0.29, P = 0.003), disease duration (β = 0.16, P = 0.033), lesion duration (β = 0.25, P = 0.003), education (β = 0.11, P = 0.024), and age (β=-0.14, P = 0.036) had indirect effects on practice. Vitiligo patients exhibited significant gaps in knowledge and attitudes toward their condition despite active management practices. Given the chronic nature of vitiligo and its slow treatment response, tailored health education strategies focusing on improving knowledge and attitudes are essential for standardizing treatment and enhancing patient adherence.https://doi.org/10.1038/s41598-025-89346-wKnowledge, attitude, practiceVitiligoSunlightCross-sectional studySurvey |
| spellingShingle | Hua Feng Xiulian Xu Shuzhen Qi Kun Chen Mei Ju Xiaofang Li Shuxian Shang Knowledge, attitude, and practice toward vitiligo among vitiligo patients: a mediation analysis Scientific Reports Knowledge, attitude, practice Vitiligo Sunlight Cross-sectional study Survey |
| title | Knowledge, attitude, and practice toward vitiligo among vitiligo patients: a mediation analysis |
| title_full | Knowledge, attitude, and practice toward vitiligo among vitiligo patients: a mediation analysis |
| title_fullStr | Knowledge, attitude, and practice toward vitiligo among vitiligo patients: a mediation analysis |
| title_full_unstemmed | Knowledge, attitude, and practice toward vitiligo among vitiligo patients: a mediation analysis |
| title_short | Knowledge, attitude, and practice toward vitiligo among vitiligo patients: a mediation analysis |
| title_sort | knowledge attitude and practice toward vitiligo among vitiligo patients a mediation analysis |
| topic | Knowledge, attitude, practice Vitiligo Sunlight Cross-sectional study Survey |
| url | https://doi.org/10.1038/s41598-025-89346-w |
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