Intelligent wearable devices with audio collection capabilities to assess chronic obstructive pulmonary disease severity
Background Intelligent wearable devices have potential for chronic obstructive pulmonary disease (COPD) monitoring, but the effectiveness of combining cough and blowing sounds for disease assessment is unclear. Objective The objective was to assess COPD severity via physiological parameters and audi...
Saved in:
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2025-03-01
|
| Series: | Digital Health |
| Online Access: | https://doi.org/10.1177/20552076251320730 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850036300316409856 |
|---|---|
| author | Chunbo Zhang Kunyao Yu Zhe Jin Yingcong Bao Cheng Zhang Jiping Liao Guangfa Wang |
| author_facet | Chunbo Zhang Kunyao Yu Zhe Jin Yingcong Bao Cheng Zhang Jiping Liao Guangfa Wang |
| author_sort | Chunbo Zhang |
| collection | DOAJ |
| description | Background Intelligent wearable devices have potential for chronic obstructive pulmonary disease (COPD) monitoring, but the effectiveness of combining cough and blowing sounds for disease assessment is unclear. Objective The objective was to assess COPD severity via physiological parameters and audio data collected by a smartwatch. Methods COPD patients underwent lung function tests, electrocardiograms, blood gas analysis, and 6-min walk tests. The patients’ peripheral arterial oxygen saturation (SpO 2 ), heart rate variability (HRV), heart rate (HR), and respiratory rate (RR) were continuously monitored via a smartwatch for 7–14 days, and voluntary cough and forceful blowing sounds were recorded twice daily. The HR, SpO 2 , and RR were categorized into all-day, sleep, and wake periods and summarized using the mean, standard deviation, median, 25th percentile, 75th percentile and percent variation. The correlations among lung function, physiological parameters, and audio data were analyzed to develop a model for predicting COPD severity. Results Twenty-nine stable patients, with a mean age of 67.0 ± 5.8 years, were enrolled, and 89.7% were male. HR, HRV, RR, cough sounds, and blowing sounds were significantly correlated with the Global Initiative for Chronic Obstructive Lung Disease (GOLD) grade, with cough sounds showing the highest correlation (r = 0.7617, p < .001). Cough sounds also had the strongest correlation with the mean 6-minute walking distance (r = 0.6847, p < .001), whereas blowing sounds had the strongest correlation with the Body mass index, airflow Obstruction, Dyspnea, and Exercise capacity index (r = −0.6749, p < .001). A logistic regression model using the RR and blowing sounds as key predictors achieved accuracies of 0.77–0.89 in determining the GOLD grade, with a Cohen's kappa coefficient of 0.6757. Conclusions Audio data were more strongly correlated with lung function in COPD patients than were physiological parameters. A smartwatch with audio collection capabilities effectively assessed COPD severity. Trial Registration ClinicalTrials.gov NCT05551169 |
| format | Article |
| id | doaj-art-4f475dda0edd4978b22c04510f9aee3f |
| institution | DOAJ |
| issn | 2055-2076 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Digital Health |
| spelling | doaj-art-4f475dda0edd4978b22c04510f9aee3f2025-08-20T02:57:13ZengSAGE PublishingDigital Health2055-20762025-03-011110.1177/20552076251320730Intelligent wearable devices with audio collection capabilities to assess chronic obstructive pulmonary disease severityChunbo ZhangKunyao YuZhe JinYingcong BaoCheng ZhangJiping LiaoGuangfa WangBackground Intelligent wearable devices have potential for chronic obstructive pulmonary disease (COPD) monitoring, but the effectiveness of combining cough and blowing sounds for disease assessment is unclear. Objective The objective was to assess COPD severity via physiological parameters and audio data collected by a smartwatch. Methods COPD patients underwent lung function tests, electrocardiograms, blood gas analysis, and 6-min walk tests. The patients’ peripheral arterial oxygen saturation (SpO 2 ), heart rate variability (HRV), heart rate (HR), and respiratory rate (RR) were continuously monitored via a smartwatch for 7–14 days, and voluntary cough and forceful blowing sounds were recorded twice daily. The HR, SpO 2 , and RR were categorized into all-day, sleep, and wake periods and summarized using the mean, standard deviation, median, 25th percentile, 75th percentile and percent variation. The correlations among lung function, physiological parameters, and audio data were analyzed to develop a model for predicting COPD severity. Results Twenty-nine stable patients, with a mean age of 67.0 ± 5.8 years, were enrolled, and 89.7% were male. HR, HRV, RR, cough sounds, and blowing sounds were significantly correlated with the Global Initiative for Chronic Obstructive Lung Disease (GOLD) grade, with cough sounds showing the highest correlation (r = 0.7617, p < .001). Cough sounds also had the strongest correlation with the mean 6-minute walking distance (r = 0.6847, p < .001), whereas blowing sounds had the strongest correlation with the Body mass index, airflow Obstruction, Dyspnea, and Exercise capacity index (r = −0.6749, p < .001). A logistic regression model using the RR and blowing sounds as key predictors achieved accuracies of 0.77–0.89 in determining the GOLD grade, with a Cohen's kappa coefficient of 0.6757. Conclusions Audio data were more strongly correlated with lung function in COPD patients than were physiological parameters. A smartwatch with audio collection capabilities effectively assessed COPD severity. Trial Registration ClinicalTrials.gov NCT05551169https://doi.org/10.1177/20552076251320730 |
| spellingShingle | Chunbo Zhang Kunyao Yu Zhe Jin Yingcong Bao Cheng Zhang Jiping Liao Guangfa Wang Intelligent wearable devices with audio collection capabilities to assess chronic obstructive pulmonary disease severity Digital Health |
| title | Intelligent wearable devices with audio collection capabilities to assess chronic obstructive pulmonary disease severity |
| title_full | Intelligent wearable devices with audio collection capabilities to assess chronic obstructive pulmonary disease severity |
| title_fullStr | Intelligent wearable devices with audio collection capabilities to assess chronic obstructive pulmonary disease severity |
| title_full_unstemmed | Intelligent wearable devices with audio collection capabilities to assess chronic obstructive pulmonary disease severity |
| title_short | Intelligent wearable devices with audio collection capabilities to assess chronic obstructive pulmonary disease severity |
| title_sort | intelligent wearable devices with audio collection capabilities to assess chronic obstructive pulmonary disease severity |
| url | https://doi.org/10.1177/20552076251320730 |
| work_keys_str_mv | AT chunbozhang intelligentwearabledeviceswithaudiocollectioncapabilitiestoassesschronicobstructivepulmonarydiseaseseverity AT kunyaoyu intelligentwearabledeviceswithaudiocollectioncapabilitiestoassesschronicobstructivepulmonarydiseaseseverity AT zhejin intelligentwearabledeviceswithaudiocollectioncapabilitiestoassesschronicobstructivepulmonarydiseaseseverity AT yingcongbao intelligentwearabledeviceswithaudiocollectioncapabilitiestoassesschronicobstructivepulmonarydiseaseseverity AT chengzhang intelligentwearabledeviceswithaudiocollectioncapabilitiestoassesschronicobstructivepulmonarydiseaseseverity AT jipingliao intelligentwearabledeviceswithaudiocollectioncapabilitiestoassesschronicobstructivepulmonarydiseaseseverity AT guangfawang intelligentwearabledeviceswithaudiocollectioncapabilitiestoassesschronicobstructivepulmonarydiseaseseverity |