MRI features of AIDS with neurosyphilis

Objective To investigate the MRI manifestations of AIDS associated with neurosyphilis and improve the understanding of this condition.Methods Data showing the imaging characteristics and clinical manifestations in patients with clinically proven AIDS associated with neurosyphilis in Bei-jing You’an...

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Main Authors: Mei-Ji REN, Li LI, Jing ZHAO, Hong-Jun LI
Format: Article
Language:zho
Published: Editorial Office of New Medicine 2022-06-01
Series:Yixue xinzhi zazhi
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Online Access:https://yxxz.whuznhmedj.com/storage/attach/2206/Py5f0jUjHsMchmUhqwA2l5hBO01RXI0qwkzB6SBZ.pdf
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author Mei-Ji REN
Li LI
Jing ZHAO
Hong-Jun LI
author_facet Mei-Ji REN
Li LI
Jing ZHAO
Hong-Jun LI
author_sort Mei-Ji REN
collection DOAJ
description Objective To investigate the MRI manifestations of AIDS associated with neurosyphilis and improve the understanding of this condition.Methods Data showing the imaging characteristics and clinical manifestations in patients with clinically proven AIDS associated with neurosyphilis in Bei-jing You’an Hospital Affiliated of Capital Medical University were collected and analyzed retrospectively.Results A total of 32 patients were included and a total of 29 lesions were found. The location of le-sions was: temporal lobe 7 cases (24.14%), basal gangli 6 cases (20.69%), frontal lobe 6 cases (20.69%), parietal lobe 3 cases (10.34%), occipital lobe 3 cases (10.34%), centrum semiovale 2 cases (6.90%) and cerebral atrophy was present in 2 cases (6.90%). According to the site of TP invasion and clinical mani-festations, the types of cases were as follows: 9 asymptomatic cases (28.12%), 2 meningeal cases (6.25%), 5 meningeal vascular cases (15.62%), 15 parenchymal cases (46.88%) and 1 gumma case (3.13%). After injection of Gd-DTPA, gyria-enhancment was detected in meningal neurosyphilis, lamella and gyria-enhancment was found in meningovascular neurosyphilis, while irregular enhancing was noted in the cerebral gumma. Cerebral atrophy was manifested in a patient with general paresis of the insane. The symptoms improved after anti-syphilis treatment.Conclusion AIDS with neurosyphilis has atypical MRI manifestations. Comprehensive analysis of imaging data and laboratory examination is helpful to assist in early diagnosis of neurosyphilis.
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spelling doaj-art-4f4644c3db3a4da5adabe8bb3d6deba22025-08-20T02:39:04ZzhoEditorial Office of New MedicineYixue xinzhi zazhi1004-55112022-06-0132317017510.12173/j.issn.1004-5511.2022030256340MRI features of AIDS with neurosyphilisMei-Ji RENLi LIJing ZHAOHong-Jun LIObjective To investigate the MRI manifestations of AIDS associated with neurosyphilis and improve the understanding of this condition.Methods Data showing the imaging characteristics and clinical manifestations in patients with clinically proven AIDS associated with neurosyphilis in Bei-jing You’an Hospital Affiliated of Capital Medical University were collected and analyzed retrospectively.Results A total of 32 patients were included and a total of 29 lesions were found. The location of le-sions was: temporal lobe 7 cases (24.14%), basal gangli 6 cases (20.69%), frontal lobe 6 cases (20.69%), parietal lobe 3 cases (10.34%), occipital lobe 3 cases (10.34%), centrum semiovale 2 cases (6.90%) and cerebral atrophy was present in 2 cases (6.90%). According to the site of TP invasion and clinical mani-festations, the types of cases were as follows: 9 asymptomatic cases (28.12%), 2 meningeal cases (6.25%), 5 meningeal vascular cases (15.62%), 15 parenchymal cases (46.88%) and 1 gumma case (3.13%). After injection of Gd-DTPA, gyria-enhancment was detected in meningal neurosyphilis, lamella and gyria-enhancment was found in meningovascular neurosyphilis, while irregular enhancing was noted in the cerebral gumma. Cerebral atrophy was manifested in a patient with general paresis of the insane. The symptoms improved after anti-syphilis treatment.Conclusion AIDS with neurosyphilis has atypical MRI manifestations. Comprehensive analysis of imaging data and laboratory examination is helpful to assist in early diagnosis of neurosyphilis.https://yxxz.whuznhmedj.com/storage/attach/2206/Py5f0jUjHsMchmUhqwA2l5hBO01RXI0qwkzB6SBZ.pdfacquired immunodeficiency syndrome neurosyphilis magnetic resonance imaging
spellingShingle Mei-Ji REN
Li LI
Jing ZHAO
Hong-Jun LI
MRI features of AIDS with neurosyphilis
Yixue xinzhi zazhi
acquired immunodeficiency syndrome
neurosyphilis
magnetic resonance imaging
title MRI features of AIDS with neurosyphilis
title_full MRI features of AIDS with neurosyphilis
title_fullStr MRI features of AIDS with neurosyphilis
title_full_unstemmed MRI features of AIDS with neurosyphilis
title_short MRI features of AIDS with neurosyphilis
title_sort mri features of aids with neurosyphilis
topic acquired immunodeficiency syndrome
neurosyphilis
magnetic resonance imaging
url https://yxxz.whuznhmedj.com/storage/attach/2206/Py5f0jUjHsMchmUhqwA2l5hBO01RXI0qwkzB6SBZ.pdf
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AT lili mrifeaturesofaidswithneurosyphilis
AT jingzhao mrifeaturesofaidswithneurosyphilis
AT hongjunli mrifeaturesofaidswithneurosyphilis