Testicular “Hyperstimulation” Syndrome: A Case of Functional Gonadotropinoma
Gonadotropins secreting pituitary tumors tend to present as sellar mass with hypogonadism. Biologically active LH secretion by these tumors resulting in elevated testosterone is extremely rare. We report a case of a 48-year-old male patient who presented with giant pituitary tumor, elevated testoste...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2014-01-01
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| Series: | Case Reports in Endocrinology |
| Online Access: | http://dx.doi.org/10.1155/2014/194716 |
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| author | Astha Thakkar Subramanian Kannan Amir Hamrahian Richard A. Prayson Robert J. Weil Charles Faiman |
| author_facet | Astha Thakkar Subramanian Kannan Amir Hamrahian Richard A. Prayson Robert J. Weil Charles Faiman |
| author_sort | Astha Thakkar |
| collection | DOAJ |
| description | Gonadotropins secreting pituitary tumors tend to present as sellar mass with hypogonadism. Biologically active LH secretion by these tumors resulting in elevated testosterone is extremely rare. We report a case of a 48-year-old male patient who presented with giant pituitary tumor, elevated testosterone, and elevated levels of gonadotropins. Surgical resection of the tumor resulted in normalization of gonadotropins and fall in serum testosterone to subnormal levels in the postoperative period confirming that the tumor was secreting bioactive luteinizing hormone (LH). |
| format | Article |
| id | doaj-art-4f39be308d6d41b586d6ff1f3e108fa1 |
| institution | OA Journals |
| issn | 2090-6501 2090-651X |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Endocrinology |
| spelling | doaj-art-4f39be308d6d41b586d6ff1f3e108fa12025-08-20T02:05:39ZengWileyCase Reports in Endocrinology2090-65012090-651X2014-01-01201410.1155/2014/194716194716Testicular “Hyperstimulation” Syndrome: A Case of Functional GonadotropinomaAstha Thakkar0Subramanian Kannan1Amir Hamrahian2Richard A. Prayson3Robert J. Weil4Charles Faiman5Topiwala National Medical College and BYL Nair Charitable Hospital, Mumbai 400008, IndiaEndocrinology, Diabetes & Metabolism Institute, Cleveland Clinic Foundation, Cleveland, OH 44195, USAEndocrinology, Diabetes & Metabolism Institute, Cleveland Clinic Foundation, Cleveland, OH 44195, USAInstitute of Anatomic Pathology, Cleveland Clinic Foundation, Cleveland, OH 44195, USABrain Tumor & Neuro-Oncology Center, Department of Neurosurgery, The Neurological Institute, Cleveland Clinic Foundation, Cleveland, OH 44195, USAEndocrinology, Diabetes & Metabolism Institute, Cleveland Clinic Foundation, Cleveland, OH 44195, USAGonadotropins secreting pituitary tumors tend to present as sellar mass with hypogonadism. Biologically active LH secretion by these tumors resulting in elevated testosterone is extremely rare. We report a case of a 48-year-old male patient who presented with giant pituitary tumor, elevated testosterone, and elevated levels of gonadotropins. Surgical resection of the tumor resulted in normalization of gonadotropins and fall in serum testosterone to subnormal levels in the postoperative period confirming that the tumor was secreting bioactive luteinizing hormone (LH).http://dx.doi.org/10.1155/2014/194716 |
| spellingShingle | Astha Thakkar Subramanian Kannan Amir Hamrahian Richard A. Prayson Robert J. Weil Charles Faiman Testicular “Hyperstimulation” Syndrome: A Case of Functional Gonadotropinoma Case Reports in Endocrinology |
| title | Testicular “Hyperstimulation” Syndrome: A Case of Functional Gonadotropinoma |
| title_full | Testicular “Hyperstimulation” Syndrome: A Case of Functional Gonadotropinoma |
| title_fullStr | Testicular “Hyperstimulation” Syndrome: A Case of Functional Gonadotropinoma |
| title_full_unstemmed | Testicular “Hyperstimulation” Syndrome: A Case of Functional Gonadotropinoma |
| title_short | Testicular “Hyperstimulation” Syndrome: A Case of Functional Gonadotropinoma |
| title_sort | testicular hyperstimulation syndrome a case of functional gonadotropinoma |
| url | http://dx.doi.org/10.1155/2014/194716 |
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