Plasmablastic transformation of a double hit follicular lymphoma: An emerging entity
Plasmablastic transformation of follicular lymphoma is very rare and has been reported in only 5 cases till date. We report a case of simultaneous identification of extranodal, soft tissue plasmablastic lymphoma in the ankle and bone marrow involvement by follicular lymphoma. This unusual case prese...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2024-04-01
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| Series: | Indian Journal of Pathology and Microbiology |
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| Online Access: | https://journals.lww.com/10.4103/ijpm.ijpm_898_21 |
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| author | Shanaz Khodaiji Vidisha Mahajan Krishna Sawaimoon Satyakam Pratibha Sudhan Kadam Amare |
| author_facet | Shanaz Khodaiji Vidisha Mahajan Krishna Sawaimoon Satyakam Pratibha Sudhan Kadam Amare |
| author_sort | Shanaz Khodaiji |
| collection | DOAJ |
| description | Plasmablastic transformation of follicular lymphoma is very rare and has been reported in only 5 cases till date. We report a case of simultaneous identification of extranodal, soft tissue plasmablastic lymphoma in the ankle and bone marrow involvement by follicular lymphoma. This unusual case presentation is a challenge for the treating physician with the patient becoming resistant to chemotherapy and succumbing to the disease within a few months of diagnosis. These cases are known to have an aggressive clinical course with very poor prognosis and survival rate of less than 6 months. This report broadens the spectrum of morphological transformation of follicular lymphoma and it may represent a new category of high-grade transformation of follicular lymphoma. |
| format | Article |
| id | doaj-art-4f37300985aa45648f7bda1548af847e |
| institution | Kabale University |
| issn | 0377-4929 0974-5130 |
| language | English |
| publishDate | 2024-04-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Pathology and Microbiology |
| spelling | doaj-art-4f37300985aa45648f7bda1548af847e2025-02-07T13:59:08ZengWolters Kluwer Medknow PublicationsIndian Journal of Pathology and Microbiology0377-49290974-51302024-04-0167241141410.4103/ijpm.ijpm_898_21Plasmablastic transformation of a double hit follicular lymphoma: An emerging entityShanaz KhodaijiVidisha MahajanKrishna Sawaimoon SatyakamPratibha Sudhan Kadam AmarePlasmablastic transformation of follicular lymphoma is very rare and has been reported in only 5 cases till date. We report a case of simultaneous identification of extranodal, soft tissue plasmablastic lymphoma in the ankle and bone marrow involvement by follicular lymphoma. This unusual case presentation is a challenge for the treating physician with the patient becoming resistant to chemotherapy and succumbing to the disease within a few months of diagnosis. These cases are known to have an aggressive clinical course with very poor prognosis and survival rate of less than 6 months. This report broadens the spectrum of morphological transformation of follicular lymphoma and it may represent a new category of high-grade transformation of follicular lymphoma.https://journals.lww.com/10.4103/ijpm.ijpm_898_21double hit lymphomaplasmablastic lymphomatransformation |
| spellingShingle | Shanaz Khodaiji Vidisha Mahajan Krishna Sawaimoon Satyakam Pratibha Sudhan Kadam Amare Plasmablastic transformation of a double hit follicular lymphoma: An emerging entity Indian Journal of Pathology and Microbiology double hit lymphoma plasmablastic lymphoma transformation |
| title | Plasmablastic transformation of a double hit follicular lymphoma: An emerging entity |
| title_full | Plasmablastic transformation of a double hit follicular lymphoma: An emerging entity |
| title_fullStr | Plasmablastic transformation of a double hit follicular lymphoma: An emerging entity |
| title_full_unstemmed | Plasmablastic transformation of a double hit follicular lymphoma: An emerging entity |
| title_short | Plasmablastic transformation of a double hit follicular lymphoma: An emerging entity |
| title_sort | plasmablastic transformation of a double hit follicular lymphoma an emerging entity |
| topic | double hit lymphoma plasmablastic lymphoma transformation |
| url | https://journals.lww.com/10.4103/ijpm.ijpm_898_21 |
| work_keys_str_mv | AT shanazkhodaiji plasmablastictransformationofadoublehitfollicularlymphomaanemergingentity AT vidishamahajan plasmablastictransformationofadoublehitfollicularlymphomaanemergingentity AT krishnasawaimoonsatyakam plasmablastictransformationofadoublehitfollicularlymphomaanemergingentity AT pratibhasudhankadamamare plasmablastictransformationofadoublehitfollicularlymphomaanemergingentity |