Efficacy of non-invasive photobiomodulation for congenital color vision deficiency: A randomized controlled trial
Background: Congenital color vision deficiency (CVD) is a prevalent ophthalmic condition for which effective therapeutic interventions remain limited. This study evaluated the efficacy of photobiomodulation (PBM) therapy in individuals with congenital CVD. Methods: A randomized, single-blind, contro...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-08-01
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| Series: | Photodiagnosis and Photodynamic Therapy |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1572100025002534 |
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| author | Nandi Bao Chunyi Jia Liang Jia |
| author_facet | Nandi Bao Chunyi Jia Liang Jia |
| author_sort | Nandi Bao |
| collection | DOAJ |
| description | Background: Congenital color vision deficiency (CVD) is a prevalent ophthalmic condition for which effective therapeutic interventions remain limited. This study evaluated the efficacy of photobiomodulation (PBM) therapy in individuals with congenital CVD. Methods: A randomized, single-blind, controlled clinical trial was conducted involving 80 participants diagnosed with red-green CVD. Participants were randomly assigned to either a PBM treatment group or a control group. Color vision performance was assessed at baseline, and after 1, 2, and 4 weeks of intervention. Statistical analyses were conducted using the Kruskal-Wallis test with Dunn’s post hoc test for multiple comparisons. Results: Color vision recognition ability demonstrated a statistically significant improvement in the PBM treatment group compared to the control group across various parameters (p < 0.05). Conclusion: Non-invasive PBM therapy significantly enhances color vision in individuals with congenital CVD, with particularly notable improvements observed in those with green CVD. |
| format | Article |
| id | doaj-art-4f2e5b334fcd4e8f97780f1d0b709e62 |
| institution | DOAJ |
| issn | 1572-1000 |
| language | English |
| publishDate | 2025-08-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Photodiagnosis and Photodynamic Therapy |
| spelling | doaj-art-4f2e5b334fcd4e8f97780f1d0b709e622025-08-20T03:02:26ZengElsevierPhotodiagnosis and Photodynamic Therapy1572-10002025-08-015410472110.1016/j.pdpdt.2025.104721Efficacy of non-invasive photobiomodulation for congenital color vision deficiency: A randomized controlled trialNandi Bao0Chunyi Jia1Liang Jia2Senior Department of Cardiology, the Sixth Medical Center, Chinese PLA General Hospital, Beijing 100048, ChinaDepartment of Medical Laboratory, Hengshui Eighth People's Hospital, Hengshui 253800, Hebei, ChinaDepartment of Ophthalmology, the First Medical Center, Chinese PLA General Hospital, Beijing 100853, China; Corresponding author.Background: Congenital color vision deficiency (CVD) is a prevalent ophthalmic condition for which effective therapeutic interventions remain limited. This study evaluated the efficacy of photobiomodulation (PBM) therapy in individuals with congenital CVD. Methods: A randomized, single-blind, controlled clinical trial was conducted involving 80 participants diagnosed with red-green CVD. Participants were randomly assigned to either a PBM treatment group or a control group. Color vision performance was assessed at baseline, and after 1, 2, and 4 weeks of intervention. Statistical analyses were conducted using the Kruskal-Wallis test with Dunn’s post hoc test for multiple comparisons. Results: Color vision recognition ability demonstrated a statistically significant improvement in the PBM treatment group compared to the control group across various parameters (p < 0.05). Conclusion: Non-invasive PBM therapy significantly enhances color vision in individuals with congenital CVD, with particularly notable improvements observed in those with green CVD.http://www.sciencedirect.com/science/article/pii/S1572100025002534Color vision testCongenital color vision deficiencyPhotobiomodulationRandomized controlled trial |
| spellingShingle | Nandi Bao Chunyi Jia Liang Jia Efficacy of non-invasive photobiomodulation for congenital color vision deficiency: A randomized controlled trial Photodiagnosis and Photodynamic Therapy Color vision test Congenital color vision deficiency Photobiomodulation Randomized controlled trial |
| title | Efficacy of non-invasive photobiomodulation for congenital color vision deficiency: A randomized controlled trial |
| title_full | Efficacy of non-invasive photobiomodulation for congenital color vision deficiency: A randomized controlled trial |
| title_fullStr | Efficacy of non-invasive photobiomodulation for congenital color vision deficiency: A randomized controlled trial |
| title_full_unstemmed | Efficacy of non-invasive photobiomodulation for congenital color vision deficiency: A randomized controlled trial |
| title_short | Efficacy of non-invasive photobiomodulation for congenital color vision deficiency: A randomized controlled trial |
| title_sort | efficacy of non invasive photobiomodulation for congenital color vision deficiency a randomized controlled trial |
| topic | Color vision test Congenital color vision deficiency Photobiomodulation Randomized controlled trial |
| url | http://www.sciencedirect.com/science/article/pii/S1572100025002534 |
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