Colorectal lymph node harvest in cancer surgery, adequacy and treatment implication: a 5-year retrospective analysis from a tertiary hospital in Ethiopia
IntroductionColorectal cancer is one of the common malignancies, and obtaining sufficient lymph nodes after surgeries is critical for staging and subsequent treatment planning. While guidelines advocate collecting at least 12 lymph nodes, insufficient lymph node sampling can have catastrophic conseq...
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Frontiers Media S.A.
2025-03-01
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| Series: | Frontiers in Gastroenterology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fgstr.2025.1503842/full |
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| author | Sirna Emana Jaleta Sirna Emana Jaleta Abdo Kedir Abafogi Tamirat Godebo Woyimo Gashahun Mekonnen Disassa Sultan Jebel Usman Abduletif Haji-Ababor Abagojam Kedir Negesso Tukeni |
| author_facet | Sirna Emana Jaleta Sirna Emana Jaleta Abdo Kedir Abafogi Tamirat Godebo Woyimo Gashahun Mekonnen Disassa Sultan Jebel Usman Abduletif Haji-Ababor Abagojam Kedir Negesso Tukeni |
| author_sort | Sirna Emana Jaleta |
| collection | DOAJ |
| description | IntroductionColorectal cancer is one of the common malignancies, and obtaining sufficient lymph nodes after surgeries is critical for staging and subsequent treatment planning. While guidelines advocate collecting at least 12 lymph nodes, insufficient lymph node sampling can have catastrophic consequences.MethodsThis was a retrospective study that looked at the parameters influencing lymph node retrieval during colorectal cancer surgery in one of tertiary hospital in Ethiopia. In this study, data from 85 patients’ records for stages I-III were analyzed and divided into two groups: adequately harvested and inadequately harvested. The association between potential factors impacting optimal harvests was analyzed.Results and discussionThe study found that the majority of cancer patients were between the ages of 34 and 53 years, in which the adequate lymph node retrieval was achieved only in 23% of cases. Procedures being performed by GI oncologic surgeons (P = 0.006, AOR;26.4), depth of invasion (AOR:14. P = 0.05), and length of specimen (AOR:5.365 P:0.045) were associated with improved adequacy of harvesting the lymph node. In conclusion, the study discovered that colorectal cancer primarily affects young people. Only a small number of participants had adequate lymph nodes harvested. The operating surgeon’s expertise, tumor characteristics, and specimen lengths were the most important elements influencing lymph node retrieval in colorectal cancer surgery in the setting. Adequate sample length, combined with better availability to more qualified operators, may improve the adequacy of harvest in guiding future treatment decisions. |
| format | Article |
| id | doaj-art-4f2cd4576b5241b88162f100222e37ad |
| institution | DOAJ |
| issn | 2813-1169 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Gastroenterology |
| spelling | doaj-art-4f2cd4576b5241b88162f100222e37ad2025-08-20T03:15:42ZengFrontiers Media S.A.Frontiers in Gastroenterology2813-11692025-03-01410.3389/fgstr.2025.15038421503842Colorectal lymph node harvest in cancer surgery, adequacy and treatment implication: a 5-year retrospective analysis from a tertiary hospital in EthiopiaSirna Emana Jaleta0Sirna Emana Jaleta1Abdo Kedir Abafogi2Tamirat Godebo Woyimo3Gashahun Mekonnen Disassa4Sultan Jebel Usman5Abduletif Haji-Ababor Abagojam6Kedir Negesso Tukeni7Department of Pathology, Jimma University, Jimma, EthiopiaDepartment of Internal Medicine, Jimma University, Jimma, EthiopiaDepartment of Pathology, Jimma University, Jimma, EthiopiaDepartment of Internal Medicine, Jimma University, Jimma, EthiopiaDepartment of Internal Medicine, Jimma University, Jimma, EthiopiaDepartment of Surgery, Jimma University, Jimma, EthiopiaDepartment of Surgery, Jimma University, Jimma, EthiopiaDepartment of Internal Medicine, Jimma University, Jimma, EthiopiaIntroductionColorectal cancer is one of the common malignancies, and obtaining sufficient lymph nodes after surgeries is critical for staging and subsequent treatment planning. While guidelines advocate collecting at least 12 lymph nodes, insufficient lymph node sampling can have catastrophic consequences.MethodsThis was a retrospective study that looked at the parameters influencing lymph node retrieval during colorectal cancer surgery in one of tertiary hospital in Ethiopia. In this study, data from 85 patients’ records for stages I-III were analyzed and divided into two groups: adequately harvested and inadequately harvested. The association between potential factors impacting optimal harvests was analyzed.Results and discussionThe study found that the majority of cancer patients were between the ages of 34 and 53 years, in which the adequate lymph node retrieval was achieved only in 23% of cases. Procedures being performed by GI oncologic surgeons (P = 0.006, AOR;26.4), depth of invasion (AOR:14. P = 0.05), and length of specimen (AOR:5.365 P:0.045) were associated with improved adequacy of harvesting the lymph node. In conclusion, the study discovered that colorectal cancer primarily affects young people. Only a small number of participants had adequate lymph nodes harvested. The operating surgeon’s expertise, tumor characteristics, and specimen lengths were the most important elements influencing lymph node retrieval in colorectal cancer surgery in the setting. Adequate sample length, combined with better availability to more qualified operators, may improve the adequacy of harvest in guiding future treatment decisions.https://www.frontiersin.org/articles/10.3389/fgstr.2025.1503842/fullcolorectal cancerlymphadenectomycancer lymph node harvestpathological tumor stagingCancer surgerieslymph node sampling |
| spellingShingle | Sirna Emana Jaleta Sirna Emana Jaleta Abdo Kedir Abafogi Tamirat Godebo Woyimo Gashahun Mekonnen Disassa Sultan Jebel Usman Abduletif Haji-Ababor Abagojam Kedir Negesso Tukeni Colorectal lymph node harvest in cancer surgery, adequacy and treatment implication: a 5-year retrospective analysis from a tertiary hospital in Ethiopia Frontiers in Gastroenterology colorectal cancer lymphadenectomy cancer lymph node harvest pathological tumor staging Cancer surgeries lymph node sampling |
| title | Colorectal lymph node harvest in cancer surgery, adequacy and treatment implication: a 5-year retrospective analysis from a tertiary hospital in Ethiopia |
| title_full | Colorectal lymph node harvest in cancer surgery, adequacy and treatment implication: a 5-year retrospective analysis from a tertiary hospital in Ethiopia |
| title_fullStr | Colorectal lymph node harvest in cancer surgery, adequacy and treatment implication: a 5-year retrospective analysis from a tertiary hospital in Ethiopia |
| title_full_unstemmed | Colorectal lymph node harvest in cancer surgery, adequacy and treatment implication: a 5-year retrospective analysis from a tertiary hospital in Ethiopia |
| title_short | Colorectal lymph node harvest in cancer surgery, adequacy and treatment implication: a 5-year retrospective analysis from a tertiary hospital in Ethiopia |
| title_sort | colorectal lymph node harvest in cancer surgery adequacy and treatment implication a 5 year retrospective analysis from a tertiary hospital in ethiopia |
| topic | colorectal cancer lymphadenectomy cancer lymph node harvest pathological tumor staging Cancer surgeries lymph node sampling |
| url | https://www.frontiersin.org/articles/10.3389/fgstr.2025.1503842/full |
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