Ozone and Ozonated Oils in Skin Diseases: A Review

Although orthodox medicine has provided a variety of topical anti-infective agents, some of them have become scarcely effective owing to antibiotic- and chemotherapeutic-resistant pathogens. For more than a century, ozone has been known to be an excellent disinfectant that nevertheless had to be use...

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Main Authors: V. Travagli, I. Zanardi, G. Valacchi, V. Bocci
Format: Article
Language:English
Published: Wiley 2010-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2010/610418
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author V. Travagli
I. Zanardi
G. Valacchi
V. Bocci
author_facet V. Travagli
I. Zanardi
G. Valacchi
V. Bocci
author_sort V. Travagli
collection DOAJ
description Although orthodox medicine has provided a variety of topical anti-infective agents, some of them have become scarcely effective owing to antibiotic- and chemotherapeutic-resistant pathogens. For more than a century, ozone has been known to be an excellent disinfectant that nevertheless had to be used with caution for its oxidizing properties. Only during the last decade it has been learned how to tame its great reactivity by precisely dosing its concentration and permanently incorporating the gas into triglycerides where gaseous ozone chemically reacts with unsaturated substrates leading to therapeutically active ozonated derivatives. Today the stability and efficacy of the ozonated oils have been already demonstrated, but owing to a plethora of commercial products, the present paper aims to analyze these derivatives suggesting the strategy to obtain products with the best characteristics.
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series Mediators of Inflammation
spelling doaj-art-4f063dba6d3f45769a896f7c466d12c12025-08-20T02:05:35ZengWileyMediators of Inflammation0962-93511466-18612010-01-01201010.1155/2010/610418610418Ozone and Ozonated Oils in Skin Diseases: A ReviewV. Travagli0I. Zanardi1G. Valacchi2V. Bocci3Dipartimento Farmaco Chimico Tecnologico, Università degli Studi di Siena, Viale Aldo Moro 2, 53100 Siena, ItalyDipartimento Farmaco Chimico Tecnologico, Università degli Studi di Siena, Viale Aldo Moro 2, 53100 Siena, ItalyDipartimento di Scienze Biomediche, Università degli Studi di Siena Viale Aldo Moro 2, 53100 Siena, ItalyDipartimento di Fisiologia, Università degli Studi di Siena, Viale Aldo Moro 2, 53100 Siena, ItalyAlthough orthodox medicine has provided a variety of topical anti-infective agents, some of them have become scarcely effective owing to antibiotic- and chemotherapeutic-resistant pathogens. For more than a century, ozone has been known to be an excellent disinfectant that nevertheless had to be used with caution for its oxidizing properties. Only during the last decade it has been learned how to tame its great reactivity by precisely dosing its concentration and permanently incorporating the gas into triglycerides where gaseous ozone chemically reacts with unsaturated substrates leading to therapeutically active ozonated derivatives. Today the stability and efficacy of the ozonated oils have been already demonstrated, but owing to a plethora of commercial products, the present paper aims to analyze these derivatives suggesting the strategy to obtain products with the best characteristics.http://dx.doi.org/10.1155/2010/610418
spellingShingle V. Travagli
I. Zanardi
G. Valacchi
V. Bocci
Ozone and Ozonated Oils in Skin Diseases: A Review
Mediators of Inflammation
title Ozone and Ozonated Oils in Skin Diseases: A Review
title_full Ozone and Ozonated Oils in Skin Diseases: A Review
title_fullStr Ozone and Ozonated Oils in Skin Diseases: A Review
title_full_unstemmed Ozone and Ozonated Oils in Skin Diseases: A Review
title_short Ozone and Ozonated Oils in Skin Diseases: A Review
title_sort ozone and ozonated oils in skin diseases a review
url http://dx.doi.org/10.1155/2010/610418
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