A Structural Optimization Framework for Biodegradable Magnesium Interference Screws
Biodegradable magnesium alloys have garnered increasing attention in recent years, with magnesium alloy–based biomedical devices being clinically used. Unlike biologically inert metallic materials, magnesium-based medical devices degrade during service, resulting in a mechanical structure that evolv...
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MDPI AG
2025-03-01
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| Series: | Biomimetics |
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| Online Access: | https://www.mdpi.com/2313-7673/10/4/210 |
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| author | Zhenquan Shen Xiaochen Zhou Ming Zhao Yafei Li |
| author_facet | Zhenquan Shen Xiaochen Zhou Ming Zhao Yafei Li |
| author_sort | Zhenquan Shen |
| collection | DOAJ |
| description | Biodegradable magnesium alloys have garnered increasing attention in recent years, with magnesium alloy–based biomedical devices being clinically used. Unlike biologically inert metallic materials, magnesium-based medical devices degrade during service, resulting in a mechanical structure that evolves over time. However, there are currently few computer-aided engineering methods specifically tailored for magnesium-based medical devices. This paper introduces a structural optimization framework for Mg-1Ca interference screws, accounting for degradation using a continuum damage model (CDM). The Optimal Latin Hypercube Sampling (OLHS) technique was employed to sample within the design space. Pull-out strengths were used as the optimization objective, which were calculated through finite element analysis (FEA). Both Response Surface Methodology (RSM) and Kriging models were employed as surrogate models and optimized using the Sequential Quadratic Programming (SQP) algorithm. The results from the Kriging model were validated through FEA, and were found to be acceptable. The relationships between the design parameters, the rationale behind the methodology, and its limitations are discussed. Finally, a final design is proposed along with recommendations for interference screw design. |
| format | Article |
| id | doaj-art-4f02162f0a454e55ad6cef864917a616 |
| institution | OA Journals |
| issn | 2313-7673 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biomimetics |
| spelling | doaj-art-4f02162f0a454e55ad6cef864917a6162025-08-20T02:24:43ZengMDPI AGBiomimetics2313-76732025-03-0110421010.3390/biomimetics10040210A Structural Optimization Framework for Biodegradable Magnesium Interference ScrewsZhenquan Shen0Xiaochen Zhou1Ming Zhao2Yafei Li3Faculty of Artificial Intelligence in Education, Central China Normal University, Wuhan 430079, ChinaSchool of Materials Science and Engineering, Peking University, Beijing 100871, ChinaSchlumberger Technology Corporation, Houston, TX 77054, USASchool of Materials Science and Engineering, Zhengzhou University, Zhengzhou 450001, ChinaBiodegradable magnesium alloys have garnered increasing attention in recent years, with magnesium alloy–based biomedical devices being clinically used. Unlike biologically inert metallic materials, magnesium-based medical devices degrade during service, resulting in a mechanical structure that evolves over time. However, there are currently few computer-aided engineering methods specifically tailored for magnesium-based medical devices. This paper introduces a structural optimization framework for Mg-1Ca interference screws, accounting for degradation using a continuum damage model (CDM). The Optimal Latin Hypercube Sampling (OLHS) technique was employed to sample within the design space. Pull-out strengths were used as the optimization objective, which were calculated through finite element analysis (FEA). Both Response Surface Methodology (RSM) and Kriging models were employed as surrogate models and optimized using the Sequential Quadratic Programming (SQP) algorithm. The results from the Kriging model were validated through FEA, and were found to be acceptable. The relationships between the design parameters, the rationale behind the methodology, and its limitations are discussed. Finally, a final design is proposed along with recommendations for interference screw design.https://www.mdpi.com/2313-7673/10/4/210biodegradationmagnesium alloysinterference screwcontinuum damage mechanicsfinite element methodstructural optimization |
| spellingShingle | Zhenquan Shen Xiaochen Zhou Ming Zhao Yafei Li A Structural Optimization Framework for Biodegradable Magnesium Interference Screws Biomimetics biodegradation magnesium alloys interference screw continuum damage mechanics finite element method structural optimization |
| title | A Structural Optimization Framework for Biodegradable Magnesium Interference Screws |
| title_full | A Structural Optimization Framework for Biodegradable Magnesium Interference Screws |
| title_fullStr | A Structural Optimization Framework for Biodegradable Magnesium Interference Screws |
| title_full_unstemmed | A Structural Optimization Framework for Biodegradable Magnesium Interference Screws |
| title_short | A Structural Optimization Framework for Biodegradable Magnesium Interference Screws |
| title_sort | structural optimization framework for biodegradable magnesium interference screws |
| topic | biodegradation magnesium alloys interference screw continuum damage mechanics finite element method structural optimization |
| url | https://www.mdpi.com/2313-7673/10/4/210 |
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