Frequency of adverse reactions during chemotherapy for genital tuberculosis in patients with infertility and high treatment adherence
The investigation enrolled 60 infertile patients diagnosed with genital tuberculosis who had completed a basic cycle of etiotropic specific antituberculosis treatment. 53.3% of the women developed adverse reactions (ARs) to anti-TB drugs. In the majority (78.1%) of the patients, chemotherapy for gen...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | Russian |
| Published: |
New Terra Publishing House
2015-01-01
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| Series: | Туберкулез и болезни лёгких |
| Subjects: | |
| Online Access: | https://www.tibl-journal.com/jour/article/view/332 |
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| Summary: | The investigation enrolled 60 infertile patients diagnosed with genital tuberculosis who had completed a basic cycle of etiotropic specific antituberculosis treatment. 53.3% of the women developed adverse reactions (ARs) to anti-TB drugs. In the majority (78.1%) of the patients, chemotherapy for genital tuberculosis was complicated by one type of ARs. In the patients with genital tuberculosis and infertility, the most common AR to anti-TB agents was drug-induced hepatitis that was noted in 62.5% of the women. Digestive comorbidity and high adherence to antituberculosis therapy favored the development of ARs in most patients. ARs to anti-TB drugs did not affect the efficiency of treatment for genital tuberculosis in infertile women; however, they contributed to longer treatment in hospital. |
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| ISSN: | 2075-1230 2542-1506 |