2-YEAR EXPERIENCE OF CORNEAL COLLAGEN CROSSLINKING IN KERATOCONUS TREATMENT

Aim. To assess reliability, efficacy, and stability of corneal collagen crosslinking (CXL) results for stage I‑II keratoconus.Patients and methods. 2‑year (2012-2014) results of CXL were analyzed. CXL was performed on 20 eyes of 15 patients (13 men and 2 women, mean age 31 years). Stage 1 keratoconu...

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Main Authors: D. D. Dement’ev, M. V. Sysoeva, A. V. Shipunova
Format: Article
Language:Russian
Published: Ophthalmology Publishing Group 2015-07-01
Series:Oftalʹmologiâ
Subjects:
Online Access:https://www.ophthalmojournal.com/opht/article/view/238
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author D. D. Dement’ev
M. V. Sysoeva
A. V. Shipunova
author_facet D. D. Dement’ev
M. V. Sysoeva
A. V. Shipunova
author_sort D. D. Dement’ev
collection DOAJ
description Aim. To assess reliability, efficacy, and stability of corneal collagen crosslinking (CXL) results for stage I‑II keratoconus.Patients and methods. 2‑year (2012-2014) results of CXL were analyzed. CXL was performed on 20 eyes of 15 patients (13 men and 2 women, mean age 31 years). Stage 1 keratoconus was diagnosed in 13 eyes, stage 2 keratoconus was diagnosed in 2 eyes. Primary stage 1‑2 keratoconus was diagnosed in 17 eyes, keratoconus after corneal refractive surgery (LASIK, radial keratotomy) was diagnosed in 3 eyes. Preoperative and postoperative examination included uncorrected (UCVA) and best-corrected (BCVA) visual acuity measurement, pachymetry, corneal topography (total astigmatism measurement), and biomicroscopy. Follow-up period varied from 1 to 24 months.Results. All patients reported on vision improvement. Preoperatively, mean UCVA and BCVA were 0.4 and 0.64, respectively. Postoperatively, mean UCVA and BCVA were 0.49 and 0.66, respectively. Preoperatively and postoperatively, total astigmatism was 2.1 D and 2.0 D, respectively, while mean central corneal thickness was 454 μm and 447 μm, respectively.Conclusions. Corneal collagen crosslinking for stage 1‑2 keratoconus provides mild UCVA and BCVA improvement, decrease in total astigmatism and central corneal thickness. CXL provides stable results of treatment of primary stage 1‑2 keratoconus and keratoconus after corneal refractive surgery.
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spelling doaj-art-4efa89136dc040f69d19ed1cd08c42ee2025-08-20T04:00:20ZrusOphthalmology Publishing GroupOftalʹmologiâ1816-50952500-08452015-07-01122313610.18008/1816-5095-2015-2-31-362332-YEAR EXPERIENCE OF CORNEAL COLLAGEN CROSSLINKING IN KERATOCONUS TREATMENTD. D. Dement’ev0M. V. Sysoeva1A. V. Shipunova2International Ophthalmological Center, MoscowInternational Ophthalmological Center, MoscowInternational Ophthalmological Center, MoscowAim. To assess reliability, efficacy, and stability of corneal collagen crosslinking (CXL) results for stage I‑II keratoconus.Patients and methods. 2‑year (2012-2014) results of CXL were analyzed. CXL was performed on 20 eyes of 15 patients (13 men and 2 women, mean age 31 years). Stage 1 keratoconus was diagnosed in 13 eyes, stage 2 keratoconus was diagnosed in 2 eyes. Primary stage 1‑2 keratoconus was diagnosed in 17 eyes, keratoconus after corneal refractive surgery (LASIK, radial keratotomy) was diagnosed in 3 eyes. Preoperative and postoperative examination included uncorrected (UCVA) and best-corrected (BCVA) visual acuity measurement, pachymetry, corneal topography (total astigmatism measurement), and biomicroscopy. Follow-up period varied from 1 to 24 months.Results. All patients reported on vision improvement. Preoperatively, mean UCVA and BCVA were 0.4 and 0.64, respectively. Postoperatively, mean UCVA and BCVA were 0.49 and 0.66, respectively. Preoperatively and postoperatively, total astigmatism was 2.1 D and 2.0 D, respectively, while mean central corneal thickness was 454 μm and 447 μm, respectively.Conclusions. Corneal collagen crosslinking for stage 1‑2 keratoconus provides mild UCVA and BCVA improvement, decrease in total astigmatism and central corneal thickness. CXL provides stable results of treatment of primary stage 1‑2 keratoconus and keratoconus after corneal refractive surgery.https://www.ophthalmojournal.com/opht/article/view/238keratoconuscorneal collagen crosslinkingkeratectasiakeratorefractive surgery
spellingShingle D. D. Dement’ev
M. V. Sysoeva
A. V. Shipunova
2-YEAR EXPERIENCE OF CORNEAL COLLAGEN CROSSLINKING IN KERATOCONUS TREATMENT
Oftalʹmologiâ
keratoconus
corneal collagen crosslinking
keratectasia
keratorefractive surgery
title 2-YEAR EXPERIENCE OF CORNEAL COLLAGEN CROSSLINKING IN KERATOCONUS TREATMENT
title_full 2-YEAR EXPERIENCE OF CORNEAL COLLAGEN CROSSLINKING IN KERATOCONUS TREATMENT
title_fullStr 2-YEAR EXPERIENCE OF CORNEAL COLLAGEN CROSSLINKING IN KERATOCONUS TREATMENT
title_full_unstemmed 2-YEAR EXPERIENCE OF CORNEAL COLLAGEN CROSSLINKING IN KERATOCONUS TREATMENT
title_short 2-YEAR EXPERIENCE OF CORNEAL COLLAGEN CROSSLINKING IN KERATOCONUS TREATMENT
title_sort 2 year experience of corneal collagen crosslinking in keratoconus treatment
topic keratoconus
corneal collagen crosslinking
keratectasia
keratorefractive surgery
url https://www.ophthalmojournal.com/opht/article/view/238
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AT mvsysoeva 2yearexperienceofcornealcollagencrosslinkinginkeratoconustreatment
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