Impact of Platelet-Rich Fibrin (PRF) Versus Freeze-Dried Bone Allograft (FDBA) on Peri-Implant Soft and Hard Tissue in Alveolar Ridge Preservation
Context: After tooth extraction, alveolar ridge preservation (ARP) is essential to maintain the hard and soft tissue dimensions for future implant placement. Two frequently employed biomaterials in ARP are freeze-dried bone allograft (FDBA) and platelet-rich fibrin (PRF), each possessing unique biol...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2024-12-01
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| Series: | Journal of Pharmacy and Bioallied Sciences |
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| Online Access: | https://journals.lww.com/10.4103/jpbs.jpbs_1036_24 |
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| author | Mohammed A. Razi Ankit Mahajan Rabia Zarrin Supratik Roy Manoj K. Singh Sharmila Kumari |
| author_facet | Mohammed A. Razi Ankit Mahajan Rabia Zarrin Supratik Roy Manoj K. Singh Sharmila Kumari |
| author_sort | Mohammed A. Razi |
| collection | DOAJ |
| description | Context:
After tooth extraction, alveolar ridge preservation (ARP) is essential to maintain the hard and soft tissue dimensions for future implant placement. Two frequently employed biomaterials in ARP are freeze-dried bone allograft (FDBA) and platelet-rich fibrin (PRF), each possessing unique biological characteristics.
Materials and Methods:
In a randomized controlled study, sixty individuals requiring ARP after tooth extraction were included. The patients were divided into two groups: Group A (n = 30) received PRF, and Group B (n = 30) received FDBA. Clinical measurements, such as soft tissue thickness, keratinized tissue width, and radiographic bone density, were recorded at baseline, three months, and six months after surgery. Cone-beam computed tomography (CBCT) was used to assess changes in hard tissue, such as the width and height of the alveolar ridge.
Results:
Group A (PRF) showed a significant increase in soft tissue thickness over six months, with an average gain of 2.5 mm (P < 0.01). In contrast, Group B (FDBA) showed a 30% increase in bone density compared to baseline (P < 0.05). Group B experienced a decrease in alveolar ridge height and width of 1.2 mm and 1.8 mm, respectively, while Group A showed a reduction of 1.6 mm and 2.3 mm.
Conclusion:
In conclusion, peri-implant soft and hard tissues benefit from both PRF and FDBA during alveolar ridge maintenance. Soft tissue thickness can be improved more effectively with PRF, while FDBA is superior for preserving hard tissue. |
| format | Article |
| id | doaj-art-4ef7c00213f24c2e9786c245731f7d31 |
| institution | Kabale University |
| issn | 0976-4879 0975-7406 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Pharmacy and Bioallied Sciences |
| spelling | doaj-art-4ef7c00213f24c2e9786c245731f7d312025-01-13T10:05:55ZengWolters Kluwer Medknow PublicationsJournal of Pharmacy and Bioallied Sciences0976-48790975-74062024-12-0116Suppl 4S3550S355210.4103/jpbs.jpbs_1036_24Impact of Platelet-Rich Fibrin (PRF) Versus Freeze-Dried Bone Allograft (FDBA) on Peri-Implant Soft and Hard Tissue in Alveolar Ridge PreservationMohammed A. RaziAnkit MahajanRabia ZarrinSupratik RoyManoj K. SinghSharmila KumariContext: After tooth extraction, alveolar ridge preservation (ARP) is essential to maintain the hard and soft tissue dimensions for future implant placement. Two frequently employed biomaterials in ARP are freeze-dried bone allograft (FDBA) and platelet-rich fibrin (PRF), each possessing unique biological characteristics. Materials and Methods: In a randomized controlled study, sixty individuals requiring ARP after tooth extraction were included. The patients were divided into two groups: Group A (n = 30) received PRF, and Group B (n = 30) received FDBA. Clinical measurements, such as soft tissue thickness, keratinized tissue width, and radiographic bone density, were recorded at baseline, three months, and six months after surgery. Cone-beam computed tomography (CBCT) was used to assess changes in hard tissue, such as the width and height of the alveolar ridge. Results: Group A (PRF) showed a significant increase in soft tissue thickness over six months, with an average gain of 2.5 mm (P < 0.01). In contrast, Group B (FDBA) showed a 30% increase in bone density compared to baseline (P < 0.05). Group B experienced a decrease in alveolar ridge height and width of 1.2 mm and 1.8 mm, respectively, while Group A showed a reduction of 1.6 mm and 2.3 mm. Conclusion: In conclusion, peri-implant soft and hard tissues benefit from both PRF and FDBA during alveolar ridge maintenance. Soft tissue thickness can be improved more effectively with PRF, while FDBA is superior for preserving hard tissue.https://journals.lww.com/10.4103/jpbs.jpbs_1036_24alveolar ridge preservationbone densityfreeze-dried bone allograftperi-implant tissuesplatelet-rich fibrinsoft tissue thickness |
| spellingShingle | Mohammed A. Razi Ankit Mahajan Rabia Zarrin Supratik Roy Manoj K. Singh Sharmila Kumari Impact of Platelet-Rich Fibrin (PRF) Versus Freeze-Dried Bone Allograft (FDBA) on Peri-Implant Soft and Hard Tissue in Alveolar Ridge Preservation Journal of Pharmacy and Bioallied Sciences alveolar ridge preservation bone density freeze-dried bone allograft peri-implant tissues platelet-rich fibrin soft tissue thickness |
| title | Impact of Platelet-Rich Fibrin (PRF) Versus Freeze-Dried Bone Allograft (FDBA) on Peri-Implant Soft and Hard Tissue in Alveolar Ridge Preservation |
| title_full | Impact of Platelet-Rich Fibrin (PRF) Versus Freeze-Dried Bone Allograft (FDBA) on Peri-Implant Soft and Hard Tissue in Alveolar Ridge Preservation |
| title_fullStr | Impact of Platelet-Rich Fibrin (PRF) Versus Freeze-Dried Bone Allograft (FDBA) on Peri-Implant Soft and Hard Tissue in Alveolar Ridge Preservation |
| title_full_unstemmed | Impact of Platelet-Rich Fibrin (PRF) Versus Freeze-Dried Bone Allograft (FDBA) on Peri-Implant Soft and Hard Tissue in Alveolar Ridge Preservation |
| title_short | Impact of Platelet-Rich Fibrin (PRF) Versus Freeze-Dried Bone Allograft (FDBA) on Peri-Implant Soft and Hard Tissue in Alveolar Ridge Preservation |
| title_sort | impact of platelet rich fibrin prf versus freeze dried bone allograft fdba on peri implant soft and hard tissue in alveolar ridge preservation |
| topic | alveolar ridge preservation bone density freeze-dried bone allograft peri-implant tissues platelet-rich fibrin soft tissue thickness |
| url | https://journals.lww.com/10.4103/jpbs.jpbs_1036_24 |
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