Response to Acute Psychophysical Stress and 24-Hour Glycemic Control in Healthy Older People
We examined the relation between stress reactivity and 24 h glycemic control in 17 inactive, healthy older people (≥60 years) under both a novel psychophysical stress and a seated control condition. Plasma cortisol was measured over the course of the stress and recovery periods. Glycemic control was...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | Journal of Aging Research |
| Online Access: | http://dx.doi.org/10.1155/2012/803864 |
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| author | Loretta DiPietro Catherine W. Yeckel Andrei Gribok |
| author_facet | Loretta DiPietro Catherine W. Yeckel Andrei Gribok |
| author_sort | Loretta DiPietro |
| collection | DOAJ |
| description | We examined the relation between stress reactivity and 24 h glycemic control in 17 inactive, healthy older people (≥60 years) under both a novel psychophysical stress and a seated control condition. Plasma cortisol was measured over the course of the stress and recovery periods. Glycemic control was determined over the subsequent 3 h from an oral glucose tolerance test (OGTT) and over 24 h via continuous glucose monitoring (CGM). We observed significant (P<0.05) elevations in perceived stress, cardiovascular activity, and peak cortisol response at 30 min (10.6±3.1 versus 8.6±2.6 μg·dL−1, resp.) during the stress compared with the control condition; however, 3 h OGTT glucose and insulin responses were similar between conditions. The CGM data suggested a 30–40 min postchallenge delay in peak glucose response and attenuated glucose clearance over the 6 h following the stress condition, but these alterations were not statistically significant. Healthy older people may demonstrate minimal disruption in metabolic resiliency following everyday psychological stress. |
| format | Article |
| id | doaj-art-4ef590f73c2d4d2fb6d3ce98779f015d |
| institution | OA Journals |
| issn | 2090-2204 2090-2212 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Aging Research |
| spelling | doaj-art-4ef590f73c2d4d2fb6d3ce98779f015d2025-08-20T02:05:35ZengWileyJournal of Aging Research2090-22042090-22122012-01-01201210.1155/2012/803864803864Response to Acute Psychophysical Stress and 24-Hour Glycemic Control in Healthy Older PeopleLoretta DiPietro0Catherine W. Yeckel1Andrei Gribok2The John B. Pierce Laboratory, Yale School of Medicine, New Haven, CT 06519, USAThe John B. Pierce Laboratory, Yale School of Medicine, New Haven, CT 06519, USABeltsville Human Nutrition Research Center, The United States Department of Agriculture, Beltsville, MD 20705, USAWe examined the relation between stress reactivity and 24 h glycemic control in 17 inactive, healthy older people (≥60 years) under both a novel psychophysical stress and a seated control condition. Plasma cortisol was measured over the course of the stress and recovery periods. Glycemic control was determined over the subsequent 3 h from an oral glucose tolerance test (OGTT) and over 24 h via continuous glucose monitoring (CGM). We observed significant (P<0.05) elevations in perceived stress, cardiovascular activity, and peak cortisol response at 30 min (10.6±3.1 versus 8.6±2.6 μg·dL−1, resp.) during the stress compared with the control condition; however, 3 h OGTT glucose and insulin responses were similar between conditions. The CGM data suggested a 30–40 min postchallenge delay in peak glucose response and attenuated glucose clearance over the 6 h following the stress condition, but these alterations were not statistically significant. Healthy older people may demonstrate minimal disruption in metabolic resiliency following everyday psychological stress.http://dx.doi.org/10.1155/2012/803864 |
| spellingShingle | Loretta DiPietro Catherine W. Yeckel Andrei Gribok Response to Acute Psychophysical Stress and 24-Hour Glycemic Control in Healthy Older People Journal of Aging Research |
| title | Response to Acute Psychophysical Stress and 24-Hour Glycemic Control in Healthy Older People |
| title_full | Response to Acute Psychophysical Stress and 24-Hour Glycemic Control in Healthy Older People |
| title_fullStr | Response to Acute Psychophysical Stress and 24-Hour Glycemic Control in Healthy Older People |
| title_full_unstemmed | Response to Acute Psychophysical Stress and 24-Hour Glycemic Control in Healthy Older People |
| title_short | Response to Acute Psychophysical Stress and 24-Hour Glycemic Control in Healthy Older People |
| title_sort | response to acute psychophysical stress and 24 hour glycemic control in healthy older people |
| url | http://dx.doi.org/10.1155/2012/803864 |
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