CENTRAL NERVOUS SYSTEM INVOLVEMENT IN ADULT ACUTE LYMPHOBLASTIC LEUKEMIA: DIAGNOSTIC TOOLS, PROPHYLAXIS AND THERAPY

CENTRAL NERVOUS SYSTEM INVOLVEMENT IN ADULT ACUTE LYMPHOBLASTIC LEUKEMIA: DIAGNOSTIC TOOLS, PROPHYLAXIS AND THERAPY

In adult patients with acute lymphoblastic leukemia (ALL), Central Nervous System (CNS) involvement is associated with a very poor prognosis. The diagnostic assessment of this condition relies on the use of neuroradiology, conventional cytology (CC) and flow cytometry (FCM). Among these approaches,...

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Main Authors: Maria Ilaria Del Principe, Luca Maurillo, Francesco Buccisano, Giuseppe Sconocchia, Mariagiovanna Cefalo, Giovanna De Santis, Ambra Di Veroli, Concetta Ditto, Daniela Nasso, Massimiliano Postorino, Marco Refrigeri, Cristina Attrotto, Giovanni Del Poeta, Sergio Amadori, Adriano Venditti
Format: Article
Language:English
Published: PAGEPress Publications 2014-11-01
Series:Mediterranean Journal of Hematology and Infectious Diseases
Subjects:
acute lymphoblastic leukemia, CNS involvement, flow cytometry, intrathecal therapy.
Online Access:http://www.mjhid.org/index.php/mjhid/article/view/2036
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