Safety and Efficacy of Oral Direct Factor Xa Inhibitors in Patients With Nephrotic Syndrome: Results From a National Retrospective Study

Safety and Efficacy of Oral Direct Factor Xa Inhibitors in Patients With Nephrotic Syndrome: Results From a National Retrospective Study

Introduction: The optimal management of thromboembolism (TE) in patients with nephrotic syndrome (NS) remains challenging. Until now, anticoagulation therapy for NS consisted of vitamin K antagonists (VKAs) or heparin. Data on direct oral anticoagulant (DOAC) use in NS are limited, and their safety...

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Main Authors: Caroline Arches, Arwa Jalal-Eddine, Dimitri Titeca-Beauport, Myriam Dao, Thierry Lobbedez, Philippe Zaoui, Christophe Masset, Dominique Bertrand, Khalil El Karoui, Henri Brenier, Hamza Sakhi, Bastien Peiffer, Vincent Audard, Nizar Joher
Format: Article
Language:English
Published: Elsevier 2025-04-01
Series:Kidney International Reports
Subjects:
bleeding
direct oral anticoagulants
nephrotic syndrome
thrombosis
Online Access:http://www.sciencedirect.com/science/article/pii/S2468024925000671
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