Primary breast angiosarcoma in postmenopausal women with a picture like Kasabach-Merritt syndrome: A case report
Introduction. Primary breast angiosarcoma is a very rare tumor and accounts for 0.04% of all breast malignant tumors and most commonly occur in young women. Kasabach-Merritt syndrome (KMS) is described as consumption coagulopathy with thrombocytopenia, and without adequate therapy almost...
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| Format: | Article |
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Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade
2021-01-01
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| Series: | Vojnosanitetski Pregled |
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| Online Access: | http://www.doiserbia.nb.rs/img/doi/0042-8450/2021/0042-84501900066C.pdf |
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| author | Ćuk Mirjana Gajanin Radoslav Marić Radmil Marić Veljko Todorović Svjetlana Vasić-Milanović Milena |
| author_facet | Ćuk Mirjana Gajanin Radoslav Marić Radmil Marić Veljko Todorović Svjetlana Vasić-Milanović Milena |
| author_sort | Ćuk Mirjana |
| collection | DOAJ |
| description | Introduction. Primary breast angiosarcoma is a very rare tumor and accounts
for 0.04% of all breast malignant tumors and most commonly occur in young
women. Kasabach-Merritt syndrome (KMS) is described as consumption
coagulopathy with thrombocytopenia, and without adequate therapy almost
certainly leads to a very fast lethal outcome. Case report. We present a
rare case of 60-year-old postmenopausal woman with metastatic primary
angiosarcoma of the breast associated with a picture like Kasabach-Merritt's
syndrome (thrombocytopenia and anemia without the coagulation factor
disorder with massive bleeding in the tumor). Conclusion. Primary breast
angiosarcoma in postmenopausal women is a very rare tumor, and may be
associated with anemia and thrombocytopenia without other laboratory
parameters for Kasabach-Merritt's syndrome. Anemia and thrombocytopenia are
refractory to standard treatment protocols, and also significantly reduces
the quality of life of these patients. The literature contains only a few
cases of Passociated with thrombocytopenia or with KMS and there are no
clear defined protocols for the treatment of these patients, which requires
the presentation of as many cases as possible. |
| format | Article |
| id | doaj-art-4eeaecc4abb74d6fa2f43077bf9ca53a |
| institution | OA Journals |
| issn | 0042-8450 2406-0720 |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade |
| record_format | Article |
| series | Vojnosanitetski Pregled |
| spelling | doaj-art-4eeaecc4abb74d6fa2f43077bf9ca53a2025-08-20T01:56:53ZengMinistry of Defence of the Republic of Serbia, University of Defence, BelgradeVojnosanitetski Pregled0042-84502406-07202021-01-0178447547810.2298/VSP180914066C0042-84501900066CPrimary breast angiosarcoma in postmenopausal women with a picture like Kasabach-Merritt syndrome: A case reportĆuk Mirjana0https://orcid.org/0000-0002-8261-414XGajanin Radoslav1Marić Radmil2Marić Veljko3Todorović Svjetlana4Vasić-Milanović Milena5University of East Sarajevo, Faculty of Medicine, Foča, Republic of Srpska, Bosnia and Herzegovina + University Hospital, Center for Laboratory Diagnosis, Foča, Republic of Srpska, Bosnia and HerzegovinaUniversity of Banja Luka, Faculty of Medicine, Banja Luka, Republic of Srpska, Bosnia and Herzegovina + University Clinical Center, Department of Pathology, Banja Luka, Republic of Srpska, Bosnia and HerzegovinaUniversity of East Sarajevo, Faculty of Medicine, Foča, Republic of Srpska, Bosnia and Herzegovina + University Hospital, Center for Laboratory Diagnosis, Foča, Republic of Srpska, Bosnia and HerzegovinaUniversity of East Sarajevo, Faculty of Medicine, Foča, Republic of Srpska, Bosnia and Herzegovina + University Hospital, Center for Laboratory Diagnosis, Foča, Republic of Srpska, Bosnia and HerzegovinaUniversity of East Sarajevo, Faculty of Medicine, Foča, Republic of Srpska, Bosnia and HerzegovinaPublic Health Hospital, Zvornik, Republic of Srpska, Bosnia and HerzegovinaIntroduction. Primary breast angiosarcoma is a very rare tumor and accounts for 0.04% of all breast malignant tumors and most commonly occur in young women. Kasabach-Merritt syndrome (KMS) is described as consumption coagulopathy with thrombocytopenia, and without adequate therapy almost certainly leads to a very fast lethal outcome. Case report. We present a rare case of 60-year-old postmenopausal woman with metastatic primary angiosarcoma of the breast associated with a picture like Kasabach-Merritt's syndrome (thrombocytopenia and anemia without the coagulation factor disorder with massive bleeding in the tumor). Conclusion. Primary breast angiosarcoma in postmenopausal women is a very rare tumor, and may be associated with anemia and thrombocytopenia without other laboratory parameters for Kasabach-Merritt's syndrome. Anemia and thrombocytopenia are refractory to standard treatment protocols, and also significantly reduces the quality of life of these patients. The literature contains only a few cases of Passociated with thrombocytopenia or with KMS and there are no clear defined protocols for the treatment of these patients, which requires the presentation of as many cases as possible.http://www.doiserbia.nb.rs/img/doi/0042-8450/2021/0042-84501900066C.pdfanemiaangiosarcomabreastkasabach-merrittsyndromethrombocytopenia |
| spellingShingle | Ćuk Mirjana Gajanin Radoslav Marić Radmil Marić Veljko Todorović Svjetlana Vasić-Milanović Milena Primary breast angiosarcoma in postmenopausal women with a picture like Kasabach-Merritt syndrome: A case report Vojnosanitetski Pregled anemia angiosarcoma breast kasabach-merritt syndrome thrombocytopenia |
| title | Primary breast angiosarcoma in postmenopausal women with a picture like Kasabach-Merritt syndrome: A case report |
| title_full | Primary breast angiosarcoma in postmenopausal women with a picture like Kasabach-Merritt syndrome: A case report |
| title_fullStr | Primary breast angiosarcoma in postmenopausal women with a picture like Kasabach-Merritt syndrome: A case report |
| title_full_unstemmed | Primary breast angiosarcoma in postmenopausal women with a picture like Kasabach-Merritt syndrome: A case report |
| title_short | Primary breast angiosarcoma in postmenopausal women with a picture like Kasabach-Merritt syndrome: A case report |
| title_sort | primary breast angiosarcoma in postmenopausal women with a picture like kasabach merritt syndrome a case report |
| topic | anemia angiosarcoma breast kasabach-merritt syndrome thrombocytopenia |
| url | http://www.doiserbia.nb.rs/img/doi/0042-8450/2021/0042-84501900066C.pdf |
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