Assessment of factors associated with mortality among tuberculosis patients attending Muhima District Hospital, Rwanda, 2015-2018

Introduction: Globally, Tuberculosis is a very serious public health problem. It is ranked as one of the ten top killer diseases worldwide. WHO estimated eight million cases were recorded in 2019, with two million related deaths every year. TB is a curable disease if the treatment is available and w...

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Main Authors: Kamayirese Eric Noël, Mukamurigo Judith, Birungi Francine, Sinayobye Jean d’Amour, Ntabanganyimana Daniel
Format: Article
Language:English
Published: African Field Epidemiology Network 2024-06-01
Series:Journal of Interventional Epidemiology and Public Health
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Online Access:https://www.afenet-journal.net/content/series/7/3/7/full/
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Summary:Introduction: Globally, Tuberculosis is a very serious public health problem. It is ranked as one of the ten top killer diseases worldwide. WHO estimated eight million cases were recorded in 2019, with two million related deaths every year. TB is a curable disease if the treatment is available and well followed up on with help in monitoring and evaluation of TB control program as major indicator. Methods: A retrospective study was conducted to assess the factors associated with TB mortality during treatment to determine the associated factors. Descriptive statistic and analytical statistics were used to compare demographic, patient behavior and clinical characteristics. Results: A total 445 registered TB patients with full complete information were included. Among them 74.83% were male, 4.94% died while were under treatment; 70.56%were aged 20 to 40 years old; 60.9% were married, 33.26% were single; the widowers were 23(5.17%) and the divorced 0.67%. 421(94.61%) were from urban areas. 42.92%, bivariate analysis showed that being a widower (OR 0.02; CI 0.00- 0.20) was significant, illiteracy and being educated at primary level were also significant (OR 0.86; CI 0.001- 0.019), (OR 0.05; CI 0.00-0.01) respectively; the adjusted odd ratio shows widowers (AOR: 0.01; 95% CI: 0.00 - 0.07; p = 0.001), are less likely to die while taking TB treatment compared with the married peoples and illiterate people or those having primary level education were less likely to be associated with tuberculosis mortality (AOR: 0.07; 95% CI: 0.01 – 0.45; p < 0.005), (AOR: 0.03; 95% CI: 0.00 – 0.18; p < 0.001). Therefore, illiterate people and those with primary level; both two were less likely to die compared to the reference group with TB. Conclusion: The tuberculosis mortality at Muhima District Hospital in the period of the study was 4.94%, lower than national rate of 6.0%, being a widower and having a low level of education and illiteracy were found as the factors associated with TB mortality. The study highlights the need for special attention to be given to the groups cited above in order to increase the adherence to the treatment and assess others factors necessary to reduce mortality due to TB not revealed by the study.
ISSN:2664-2824