Adolescent alcohol exposure promotes mechanical allodynia and alters synaptic function at inputs from the basolateral amygdala to the prelimbic cortex

Adolescent alcohol exposure promotes mechanical allodynia and alters synaptic function at inputs from the basolateral amygdala to the prelimbic cortex

Binge drinking is common among adolescents despite mounting evidence linking it to various adverse health outcomes that include heightened pain perception. The prelimbic (PrL) cortex is vulnerable to insult from adolescent alcohol exposure and receives input from the basolateral amygdala (BLA) while...

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Bibliographic Details
Main Authors: J Daniel Obray, Erik T Wilkes, Mike Scofield, L Judson Chandler
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2025-05-01
Series:eLife
Subjects:
adolescent alcohol
AIE
pain
allodynia
prefrontal cortex
periaqueductal gray
Online Access:https://elifesciences.org/articles/101667
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