Androgen Receptor and Tumor-Associated Neutrophil Expression Across Breast Cancer Subtypes: Associations With Clinicopathological Characteristics
Conclusion: AR is a defining marker for HR-positive breast cancers and may serve as an indicator of lower tumor grade and differentiation status. TANs, however, are linked to more aggressive phenotypes, especially in TNBC, suggesting a role in driving tumor progression. This highlights the potential...
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| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2025-01-01
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| Series: | International Journal of Breast Cancer |
| Online Access: | http://dx.doi.org/10.1155/ijbc/8209394 |
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| _version_ | 1849420993725988864 |
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| author | Minoosh Moghimi Shahin Vadoudi Majid Amirian Farzane Ahmadi Mohammad Borna Amirian Kasra Khodadadi Reza Mansouri Mahsa Mahjani Sepehr Gohari |
| author_facet | Minoosh Moghimi Shahin Vadoudi Majid Amirian Farzane Ahmadi Mohammad Borna Amirian Kasra Khodadadi Reza Mansouri Mahsa Mahjani Sepehr Gohari |
| author_sort | Minoosh Moghimi |
| collection | DOAJ |
| description | Conclusion: AR is a defining marker for HR-positive breast cancers and may serve as an indicator of lower tumor grade and differentiation status. TANs, however, are linked to more aggressive phenotypes, especially in TNBC, suggesting a role in driving tumor progression. This highlights the potential for AR and TAN expression patterns to refine patient stratification across breast cancer subtypes. |
| format | Article |
| id | doaj-art-4ec9ccfb177d4ceaa273feb20a534ceb |
| institution | Kabale University |
| issn | 2090-3189 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Breast Cancer |
| spelling | doaj-art-4ec9ccfb177d4ceaa273feb20a534ceb2025-08-20T03:31:34ZengWileyInternational Journal of Breast Cancer2090-31892025-01-01202510.1155/ijbc/8209394Androgen Receptor and Tumor-Associated Neutrophil Expression Across Breast Cancer Subtypes: Associations With Clinicopathological CharacteristicsMinoosh Moghimi0Shahin Vadoudi1Majid Amirian2Farzane Ahmadi3Mohammad Borna Amirian4Kasra Khodadadi5Reza Mansouri6Mahsa Mahjani7Sepehr Gohari8Department of Hematology-OncologyDepartment of Internal MedicineBorna Research and Medical LaboratoryDepartment of Biostatistics and EpidemiologyBorna Research and Medical LaboratoryDepartment of GastroenterologyDepartment of Hematology-OncologyEndocrine Research CenterStudent Research CenterConclusion: AR is a defining marker for HR-positive breast cancers and may serve as an indicator of lower tumor grade and differentiation status. TANs, however, are linked to more aggressive phenotypes, especially in TNBC, suggesting a role in driving tumor progression. This highlights the potential for AR and TAN expression patterns to refine patient stratification across breast cancer subtypes.http://dx.doi.org/10.1155/ijbc/8209394 |
| spellingShingle | Minoosh Moghimi Shahin Vadoudi Majid Amirian Farzane Ahmadi Mohammad Borna Amirian Kasra Khodadadi Reza Mansouri Mahsa Mahjani Sepehr Gohari Androgen Receptor and Tumor-Associated Neutrophil Expression Across Breast Cancer Subtypes: Associations With Clinicopathological Characteristics International Journal of Breast Cancer |
| title | Androgen Receptor and Tumor-Associated Neutrophil Expression Across Breast Cancer Subtypes: Associations With Clinicopathological Characteristics |
| title_full | Androgen Receptor and Tumor-Associated Neutrophil Expression Across Breast Cancer Subtypes: Associations With Clinicopathological Characteristics |
| title_fullStr | Androgen Receptor and Tumor-Associated Neutrophil Expression Across Breast Cancer Subtypes: Associations With Clinicopathological Characteristics |
| title_full_unstemmed | Androgen Receptor and Tumor-Associated Neutrophil Expression Across Breast Cancer Subtypes: Associations With Clinicopathological Characteristics |
| title_short | Androgen Receptor and Tumor-Associated Neutrophil Expression Across Breast Cancer Subtypes: Associations With Clinicopathological Characteristics |
| title_sort | androgen receptor and tumor associated neutrophil expression across breast cancer subtypes associations with clinicopathological characteristics |
| url | http://dx.doi.org/10.1155/ijbc/8209394 |
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