Clinical Characteristics and Co-morbidities in Patients with Psoriatic Arthritis
Introduction: Psoriatic Arthritis (PsA) is a chronic inflammatory arthritis and occurs in association with psoriasis, a chronic recurring and disfiguring skin disease. There is increasing recognition that both conditions are associated with multitude of co-morbidities. Objective: To delineate the...
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Society of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON)
2017-08-01
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| Series: | Nepal Journal of Dermatology, Venereology & Leprology |
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| Online Access: | https://nepjol.info/index.php/NJDVL/article/view/18052 |
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| author | Buddhi Prasad Paudyal M Gyawalee |
| author_facet | Buddhi Prasad Paudyal M Gyawalee |
| author_sort | Buddhi Prasad Paudyal |
| collection | DOAJ |
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Introduction: Psoriatic Arthritis (PsA) is a chronic inflammatory arthritis and occurs in association with psoriasis, a chronic recurring and disfiguring skin disease. There is increasing recognition that both conditions are associated with multitude of co-morbidities.
Objective: To delineate the clinical characteristics and co-morbidities in PsA patients attending a rheumatology clinic in Kathmandu valley.
Material and Methods: Patients with already developed psoriasis who were seeking medical attention for arthritis during the period between January 2013 to December 2015 were prospectively enrolled. Patients were evaluated both by a dermatologist and a rheumatologist. A structured format was used to record relevant clinical information on psoriasis, PsA, and co-morbidities.
Results: Among 55 patients with PsA, all were found to have plaque psoriasis mainly affecting extensor surfaces (64%), multiple areas (16%), and scalp (11%). Nail involvement was observed in 22% of patients. Symmetric polyarthritis was the most frequent (26%) form, followed by oligoarthrtis (18%), distal interphalangeal (DIP) joint arthritis (16%),
spondyloarthritis (13%), and enthesitis-dactylitis (7%). Two thirds of patients were either overweight or obese. Almost half (47%) were current or past smokers. Diabetes or pre-diabetes was observed in 7% of cases. Hypertension, hyperlipidemia and ischemic heart disease (IHD) were present in 20%, 16%, and 5% respectively. Fatty liver disease was observed in 13% of the tested patients and 15% of patients were on some psychotropic drugs.
Conclusion: Psoriasis with PsA was associated with both cardiovascular and non-cardiovascular co-morbidities. Doctors treating patients with these disorders should consider associated co-morbidities for better patient outcome.
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| format | Article |
| id | doaj-art-4ebf6cc0abd84e8f8e52a25ef34a6eef |
| institution | Kabale University |
| issn | 2091-0231 2091-167X |
| language | English |
| publishDate | 2017-08-01 |
| publisher | Society of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON) |
| record_format | Article |
| series | Nepal Journal of Dermatology, Venereology & Leprology |
| spelling | doaj-art-4ebf6cc0abd84e8f8e52a25ef34a6eef2025-08-24T10:06:28ZengSociety of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON)Nepal Journal of Dermatology, Venereology & Leprology2091-02312091-167X2017-08-01151Clinical Characteristics and Co-morbidities in Patients with Psoriatic ArthritisBuddhi Prasad Paudyal0M Gyawalee1Patan Academy of Health Sciences, LalitpurPatan Academy of Health Sciences, Lalitpur Introduction: Psoriatic Arthritis (PsA) is a chronic inflammatory arthritis and occurs in association with psoriasis, a chronic recurring and disfiguring skin disease. There is increasing recognition that both conditions are associated with multitude of co-morbidities. Objective: To delineate the clinical characteristics and co-morbidities in PsA patients attending a rheumatology clinic in Kathmandu valley. Material and Methods: Patients with already developed psoriasis who were seeking medical attention for arthritis during the period between January 2013 to December 2015 were prospectively enrolled. Patients were evaluated both by a dermatologist and a rheumatologist. A structured format was used to record relevant clinical information on psoriasis, PsA, and co-morbidities. Results: Among 55 patients with PsA, all were found to have plaque psoriasis mainly affecting extensor surfaces (64%), multiple areas (16%), and scalp (11%). Nail involvement was observed in 22% of patients. Symmetric polyarthritis was the most frequent (26%) form, followed by oligoarthrtis (18%), distal interphalangeal (DIP) joint arthritis (16%), spondyloarthritis (13%), and enthesitis-dactylitis (7%). Two thirds of patients were either overweight or obese. Almost half (47%) were current or past smokers. Diabetes or pre-diabetes was observed in 7% of cases. Hypertension, hyperlipidemia and ischemic heart disease (IHD) were present in 20%, 16%, and 5% respectively. Fatty liver disease was observed in 13% of the tested patients and 15% of patients were on some psychotropic drugs. Conclusion: Psoriasis with PsA was associated with both cardiovascular and non-cardiovascular co-morbidities. Doctors treating patients with these disorders should consider associated co-morbidities for better patient outcome. https://nepjol.info/index.php/NJDVL/article/view/18052psoriatic arthritisco-morbiditiesNepal |
| spellingShingle | Buddhi Prasad Paudyal M Gyawalee Clinical Characteristics and Co-morbidities in Patients with Psoriatic Arthritis Nepal Journal of Dermatology, Venereology & Leprology psoriatic arthritis co-morbidities Nepal |
| title | Clinical Characteristics and Co-morbidities in Patients with Psoriatic Arthritis |
| title_full | Clinical Characteristics and Co-morbidities in Patients with Psoriatic Arthritis |
| title_fullStr | Clinical Characteristics and Co-morbidities in Patients with Psoriatic Arthritis |
| title_full_unstemmed | Clinical Characteristics and Co-morbidities in Patients with Psoriatic Arthritis |
| title_short | Clinical Characteristics and Co-morbidities in Patients with Psoriatic Arthritis |
| title_sort | clinical characteristics and co morbidities in patients with psoriatic arthritis |
| topic | psoriatic arthritis co-morbidities Nepal |
| url | https://nepjol.info/index.php/NJDVL/article/view/18052 |
| work_keys_str_mv | AT buddhiprasadpaudyal clinicalcharacteristicsandcomorbiditiesinpatientswithpsoriaticarthritis AT mgyawalee clinicalcharacteristicsandcomorbiditiesinpatientswithpsoriaticarthritis |