Dexamethasone prevents granulocyte-macrophage colony-stimulating factor-induced nuclear factor-κB activation, inducible nitric oxide synthase expression and nitric oxide production in a skin dendritic cell line

Dexamethasone prevents granulocyte-macrophage colony-stimulating factor-induced nuclear factor-κB activation, inducible nitric oxide synthase expression and nitric oxide production in a skin dendritic cell line

Aims: Nitric oxide (NO) has been increasingly implicated in inflammatory skin diseases, namely in allergic contact dermatitis. In this work, we investigated the effect of dexamethasone on NO production induced by the epidermal cytokine granulocyte-macrophage colony-stimulating factor (GM-CSF) in a m...

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Bibliographic Details
Main Authors: Ana Luísa Vital, Margarida Gonçalo, M. Teresa Cruz, Américo Figueiredo, Carlos B. Duarte, M. Celeste Lopes
Format: Article
Language:English
Published: Wiley 2003-01-01
Series:Mediators of Inflammation
Subjects:
Granulocyte-macrophage colony-stimulating factor
Nitric oxide
Transcription factors
Dexamethasone
Skin dendritic cell.
Online Access:http://dx.doi.org/10.1080/0962935031000097673
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