Engineering biology applications for environmental solutions: potential and challenges

Abstract Engineering biology applies synthetic biology to address global environmental challenges like bioremediation, biosequestration, pollutant monitoring, and resource recovery. This perspective outlines innovations in engineering biology, its integration with other technologies (e.g., nanotechn...

Full description

Saved in:
Bibliographic Details
Main Authors: David J. Lea-Smith, Francis Hassard, Frederic Coulon, Natalie Partridge, Louise Horsfall, Kyle D. J. Parker, Robert D. J. Smith, Ronan R. McCarthy, Boyd McKew, Tony Gutierrez, Vinod Kumar, Gabriella Dotro, Zhugen Yang, EBIC partners, Natalio Krasnogor
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-58492-0
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1850181883047968768
author David J. Lea-Smith
Francis Hassard
Frederic Coulon
Natalie Partridge
Louise Horsfall
Kyle D. J. Parker
Robert D. J. Smith
Ronan R. McCarthy
Boyd McKew
Tony Gutierrez
Vinod Kumar
Gabriella Dotro
Zhugen Yang
EBIC partners
Natalio Krasnogor
author_facet David J. Lea-Smith
Francis Hassard
Frederic Coulon
Natalie Partridge
Louise Horsfall
Kyle D. J. Parker
Robert D. J. Smith
Ronan R. McCarthy
Boyd McKew
Tony Gutierrez
Vinod Kumar
Gabriella Dotro
Zhugen Yang
EBIC partners
Natalio Krasnogor
author_sort David J. Lea-Smith
collection DOAJ
description Abstract Engineering biology applies synthetic biology to address global environmental challenges like bioremediation, biosequestration, pollutant monitoring, and resource recovery. This perspective outlines innovations in engineering biology, its integration with other technologies (e.g., nanotechnology, IoT, AI), and commercial ventures leveraging these advancements. We also discuss commercialisation and scaling challenges, biosafety and biosecurity considerations including biocontainment strategies, social and political dimensions, and governance issues that must be addressed for successful real-world implementation. Finally, we highlight future perspectives and propose strategies to overcome existing hurdles, aiming to accelerate the adoption of engineering biology for environmental solutions.
format Article
id doaj-art-4eaaaac601de4667a00a1be7e8116406
institution OA Journals
issn 2041-1723
language English
publishDate 2025-04-01
publisher Nature Portfolio
record_format Article
series Nature Communications
spelling doaj-art-4eaaaac601de4667a00a1be7e81164062025-08-20T02:17:48ZengNature PortfolioNature Communications2041-17232025-04-0116111210.1038/s41467-025-58492-0Engineering biology applications for environmental solutions: potential and challengesDavid J. Lea-Smith0Francis Hassard1Frederic Coulon2Natalie Partridge3Louise Horsfall4Kyle D. J. Parker5Robert D. J. Smith6Ronan R. McCarthy7Boyd McKew8Tony Gutierrez9Vinod Kumar10Gabriella Dotro11Zhugen Yang12EBIC partners13Natalio Krasnogor14University of East AngliaCranfield UniversityCranfield UniversityGitLife Biotech LtdUniversity of EdinburghUniversity of EdinburghUniversity of EdinburghBrunel University LondonUniversity of EssexHeriot-Watt UniversityCranfield UniversityCranfield UniversityCranfield UniversityEnvironmental Biotechnology Innovation CentreGitLife Biotech LtdAbstract Engineering biology applies synthetic biology to address global environmental challenges like bioremediation, biosequestration, pollutant monitoring, and resource recovery. This perspective outlines innovations in engineering biology, its integration with other technologies (e.g., nanotechnology, IoT, AI), and commercial ventures leveraging these advancements. We also discuss commercialisation and scaling challenges, biosafety and biosecurity considerations including biocontainment strategies, social and political dimensions, and governance issues that must be addressed for successful real-world implementation. Finally, we highlight future perspectives and propose strategies to overcome existing hurdles, aiming to accelerate the adoption of engineering biology for environmental solutions.https://doi.org/10.1038/s41467-025-58492-0
spellingShingle David J. Lea-Smith
Francis Hassard
Frederic Coulon
Natalie Partridge
Louise Horsfall
Kyle D. J. Parker
Robert D. J. Smith
Ronan R. McCarthy
Boyd McKew
Tony Gutierrez
Vinod Kumar
Gabriella Dotro
Zhugen Yang
EBIC partners
Natalio Krasnogor
Engineering biology applications for environmental solutions: potential and challenges
Nature Communications
title Engineering biology applications for environmental solutions: potential and challenges
title_full Engineering biology applications for environmental solutions: potential and challenges
title_fullStr Engineering biology applications for environmental solutions: potential and challenges
title_full_unstemmed Engineering biology applications for environmental solutions: potential and challenges
title_short Engineering biology applications for environmental solutions: potential and challenges
title_sort engineering biology applications for environmental solutions potential and challenges
url https://doi.org/10.1038/s41467-025-58492-0
work_keys_str_mv AT davidjleasmith engineeringbiologyapplicationsforenvironmentalsolutionspotentialandchallenges
AT francishassard engineeringbiologyapplicationsforenvironmentalsolutionspotentialandchallenges
AT fredericcoulon engineeringbiologyapplicationsforenvironmentalsolutionspotentialandchallenges
AT nataliepartridge engineeringbiologyapplicationsforenvironmentalsolutionspotentialandchallenges
AT louisehorsfall engineeringbiologyapplicationsforenvironmentalsolutionspotentialandchallenges
AT kyledjparker engineeringbiologyapplicationsforenvironmentalsolutionspotentialandchallenges
AT robertdjsmith engineeringbiologyapplicationsforenvironmentalsolutionspotentialandchallenges
AT ronanrmccarthy engineeringbiologyapplicationsforenvironmentalsolutionspotentialandchallenges
AT boydmckew engineeringbiologyapplicationsforenvironmentalsolutionspotentialandchallenges
AT tonygutierrez engineeringbiologyapplicationsforenvironmentalsolutionspotentialandchallenges
AT vinodkumar engineeringbiologyapplicationsforenvironmentalsolutionspotentialandchallenges
AT gabrielladotro engineeringbiologyapplicationsforenvironmentalsolutionspotentialandchallenges
AT zhugenyang engineeringbiologyapplicationsforenvironmentalsolutionspotentialandchallenges
AT ebicpartners engineeringbiologyapplicationsforenvironmentalsolutionspotentialandchallenges
AT nataliokrasnogor engineeringbiologyapplicationsforenvironmentalsolutionspotentialandchallenges