PATHOGENETIC MECHANISMS OF LEPTIN RESISTANCE

PATHOGENETIC MECHANISMS OF LEPTIN RESISTANCE

Leptin is a regulatory protein from adipokines family, that maintain energy homeostasis of the body and deter obesity development. Impaired transfer of leptin signals to hypothalamus leads to leptin resistance and its adverse complications. Understanding of leptin resistance mechanisms is pivotal fo...

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Bibliographic Details
Main Authors: G. A. Chumakova, A. V. Ott, N. G. Veselovskaya, O. V. Gritsenko, N. N. Shenkova
Format: Article
Language:Russian
Published: «FIRMA «SILICEA» LLC 2015-04-01
Series:Российский кардиологический журнал
Subjects:
leptin
leptin resistance
leptin receptors
Online Access:https://russjcardiol.elpub.ru/jour/article/view/294
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Summary:Leptin is a regulatory protein from adipokines family, that maintain energy homeostasis of the body and deter obesity development. Impaired transfer of leptin signals to hypothalamus leads to leptin resistance and its adverse complications. Understanding of leptin resistance mechanisms is pivotal for the development of preventive and treatment procedures aiming to decrease the risk of atherosclerosis,
ISSN:1560-4071
2618-7620

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