Machine Learning for Precision Health Economics and Outcomes Research (P-HEOR): Conceptual Review of Applications and Next Steps

Precision health economics and outcomes research (P-HEOR) integrates economic and clinical value assessment by explicitly discovering distinct clinical and health care utilization phenotypes among patients. Through a conceptualized example, the objective of this review is to highlight the capabiliti...

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Bibliographic Details
Main Authors: Yixi Chen, Viktor V Chirikov, Xiaocong L Marston, Jingang Yang, Haibo Qiu, Jianfeng Xie, Ning Sun, Chengming Gu, Peng Dong, Xin Gao
Format: Article
Language:English
Published: Columbia Data Analytics, LLC 2020-05-01
Series:Journal of Health Economics and Outcomes Research
Online Access:https://doi.org/10.36469/jheor.2020.12698
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Summary:Precision health economics and outcomes research (P-HEOR) integrates economic and clinical value assessment by explicitly discovering distinct clinical and health care utilization phenotypes among patients. Through a conceptualized example, the objective of this review is to highlight the capabilities and limitations of machine learning (ML) applications to P-HEOR and to contextualize the potential opportunities and challenges for the wide adoption of ML for health economics. We outline a P-HEOR conceptual framework extending the ML methodology to comparatively assess the economic value of treatment regimens. Latest methodology developments on bias and confounding control in ML applications to precision medicine are also summarized.
ISSN:2327-2236