Single-cell RNA sequencing reveals the critical role of alternative splicing in cattle testicular spermatagonia

Single-cell RNA sequencing reveals the critical role of alternative splicing in cattle testicular spermatagonia

Abstract Spermatogonial stem cells (SSCs) form haploid gametes through the precisely regulated process of spermatogenesis. Within the testis, SSCs undergo self-renewal through mitosis, differentiation, and then enter meiosis to generate mature spermatids. This study utilized single-cell RNA sequenci...

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Bibliographic Details
Main Authors: Xiuge Wang, Chunhong Yang, Xiaochao Wei, Yaran Zhang, Yao Xiao, Jinpeng Wang, Qiang Jiang, Zhihua Ju, Yaping Gao, Yanqin Li, Yundong Gao, Jinming Huang
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Biology Direct
Subjects:
Alternative splicing
Cattle
Single-cell RNA sequencing
Spermatogonia
Online Access:https://doi.org/10.1186/s13062-024-00579-7
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